Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCRL2 | O00421 | 19/20 | 1.00 |
| ▸ | CCR2 | P41597 | 12/20 | 1.00 |
| ▸ | KCNH2 | Q12809 | 7/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16908753 | 1.00 | CCRL2 (1.00) | CCRL2CCR2KCNH2 | |
| SCHEMBL12053066 | 1.00 | CCRL2 (1.00) | CCRL2CCR2KCNH2 | |
| Citric Acid SCHEMBL9999027 | 0.94 | CCRL2 (0.89) | CCRL2CCR2KCNH2 | |
| Citric Acid SCHEMBL9999025 | 0.94 | CCRL2 (0.89) | CCRL2CCR2KCNH2 | |
| SCHEMBL9999374 | 0.91 | CCRL2 (1.00) | CCRL2CCR2KCNH2 | |
| SCHEMBL15214714 | 0.91 | CCRL2 (1.00) | CCRL2CCR2KCNH2 | |
| SCHEMBL9999375 | 0.91 | CCRL2 (1.00) | CCRL2CCR2KCNH2 | |
| SCHEMBL12052970 | 0.91 | CCRL2 (1.00) | CCRL2CCR2KCNH2 | |
| SCHEMBL9999360 | 0.89 | CCRL2 (1.00) | CCRL2CCR2KCNH2 | |
| SCHEMBL9999061 | 0.89 | CCRL2 (0.80) | CCRL2CCR2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2582692-B1 | CYCLOHEXYL-AZETIDINYL ANTAGONISTS OF CCR2 | JANSSEN PHARMACEUTICA NV (BE) | 2015-07-22 | — | — | EP | claimed |