SCHEMBL16908795

SCHEMBL16908795

[CH2]C1CCC(N2CC(NC(=O)CNc3ncnc4ccc(C(F)(F)F)cc34)C2)CC1

nearest known ligand 0.85

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CCRL2 O00421 20/20 0.85

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16908796 1.00 CCRL2 (0.85) CCRL2
SCHEMBL15214666 0.92 CCRL2 (1.00) CCRL2
SCHEMBL9999461 0.92 CCRL2 (1.00) CCRL2
SCHEMBL9999460 0.92 CCRL2 (1.00) CCRL2
SCHEMBL16908785 0.91 CCRL2 (0.85) CCRL2
SCHEMBL12052939 0.91 CCRL2 (0.85) CCRL2
SCHEMBL9999295 0.91 CCRL2 (1.00) CCRL2
SCHEMBL15214710 0.91 CCRL2 (1.00) CCRL2
SCHEMBL9999211 0.91 CCRL2 (1.00) CCRL2
SCHEMBL9999169 0.91 CCRL2 (1.00) CCRL2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2582692-B1 CYCLOHEXYL-AZETIDINYL ANTAGONISTS OF CCR2 JANSSEN PHARMACEUTICA NV (BE) 2015-07-22 EP claimed