Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 8/20 | 0.42 |
| ▸ | FEN1 | P39748 | 8/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | NOS3 | P29474 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16915372 | 0.82 | KMT2A (0.49) | ALOX5APFEN1HPGDKDM4EALDH1A1 | |
| SCHEMBL31532183 | 0.82 | KMT2A (0.49) | ALOX5APFEN1HPGDKDM4EALDH1A1 | |
| SCHEMBL16915377 | 0.81 | ALOX5AP (0.45) | ALOX5APFEN1HPGDKDM4EALDH1A1 | |
| SCHEMBL31532178 | 0.81 | ALOX5AP (0.45) | ALOX5APFEN1HPGDKDM4EALDH1A1 | |
| SCHEMBL16915388 | 0.78 | SCN9A (0.38) | ALOX5APFEN1HPGDKDM4EKMT2A | |
| SCHEMBL31532175 | 0.78 | SCN9A (0.38) | ALOX5APFEN1HPGDKDM4EKMT2A | |
| SCHEMBL31403297 | 0.77 | CXCR1 (0.38) | ALOX5APFEN1HPGDKDM4EALDH1A1 | |
| SCHEMBL16915394 | 0.77 | CXCR1 (0.38) | ALOX5APFEN1HPGDKDM4EALDH1A1 | |
| SCHEMBL972297 | 0.75 | HSD11B1 (0.45) | HPGDP2RX7NOS3NOS2NPC1 | |
| SCHEMBL16915375 | 0.74 | CYP1A2 (0.41) | ALOX5APFEN1LMNAPOLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111574510-B | Pyrimidine as herbicide Oxyphenyl derivatives | FMC 公司 | 2025-03-07 | — | — | CN | disclosed |
| US-11447476-B2 | Pyrimidinyloxy benzene derivatives as herbicides | FMC CORPORATION (US) | 2022-09-20 | — | — | US | disclosed |
| US-20200270238-A1 | PYRIMIDINYLOXY BENZENE DERIVATIVES AS HERBICIDES | FMC CORP (US) | 2020-08-27 | — | — | US | disclosed |
| CN-111574510-A | Pyrimidinyloxybenzene derivatives as herbicides | FMC 公司 | 2020-08-25 | — | — | CN | disclosed |
| CN-105916849-B | Pyrimidinyloxybenzene derivatives as herbicides | FMC公司 | 2020-07-07 | — | — | CN | disclosed |
| US-10654840-B2 | Pyrimidinyloxy benzene derivatives as herbicides | FMC CORPORATION (US) | 2020-05-19 | — | — | US | disclosed |
| US-20190084972-A1 | PYRIMIDINYLOXY BENZENE DERIVATIVES AS HERBICIDES | FMC CORP (US) | 2019-03-21 | — | — | US | disclosed |
| EP-3094631-B1 | PYRIMIDINYLOXY BENZENE DERIVATIVES AS HERBICIDES | FMC CORP (US) | 2019-01-09 | — | — | EP | disclosed |
| US-10131652-B2 | Pyrimidinyloxy benzene derivatives as herbicides | FMC CORPORATION | 2018-11-20 | — | — | US | disclosed |
| EP-3094631-A1 | PYRIMIDINYLOXY BENZENE DERIVATIVES AS HERBICIDES | E. I. du Pont de Nemours and Company (US) | 2016-11-23 | — | — | EP | disclosed |
| US-20160333000-A1 | PYRIMIDINYLOXY BENZENE DERIVATIVES AS HERBICIDES | FMC CORPORATION | 2016-11-17 | — | — | US | disclosed |
| WO-2015108779-A1 | PYRIMIDINYLOXY BENZENE DERIVATIVES AS HERBICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2015-07-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10131652-B2 | Pyrimidinyloxy benzene derivatives as herbicides | DDT, NQO2, CBR3 | ALOX5AP 1331/4885FEN1 663/4885HPGD 734/4885 |
| US-10654840-B2 | Pyrimidinyloxy benzene derivatives as herbicides | DDT, NQO2, CBR3 | ALOX5AP 1331/4885FEN1 663/4885HPGD 734/4885 |
| US-20200270238-A1 | PYRIMIDINYLOXY BENZENE DERIVATIVES AS HERBICIDES | DDT, NQO2, CBR3 | ALOX5AP 1331/4885FEN1 663/4885HPGD 734/4885 |
| US-20160333000-A1 | PYRIMIDINYLOXY BENZENE DERIVATIVES AS HERBICIDES | DDT, NQO2, CBR3 | ALOX5AP 1331/4885FEN1 663/4885HPGD 734/4885 |
| US-11447476-B2 | Pyrimidinyloxy benzene derivatives as herbicides | DDT, NQO2, CBR3 | ALOX5AP 1331/4885FEN1 663/4885HPGD 734/4885 |
| US-20190084972-A1 | PYRIMIDINYLOXY BENZENE DERIVATIVES AS HERBICIDES | DDT, NQO2, CBR3 | ALOX5AP 1331/4885FEN1 663/4885HPGD 734/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.