Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2405850 | 0.75 | ALDH1A1 (0.38) | ALDH1A1TDP1 | |
| SCHEMBL19262269 | 0.74 | — | — | |
| SCHEMBL23085006 | 0.70 | ESR2 (0.32) | ALDH1A1 | |
| SCHEMBL10768620 | 0.70 | ESR2 (0.32) | ALDH1A1 | |
| SCHEMBL15728043 | 0.70 | — | — | |
| SCHEMBL466014 | 0.70 | ALDH1A1 (0.34) | ALDH1A1TDP1 | |
| SCHEMBL3470683 | 0.70 | ALDH1A1 (0.34) | ALDH1A1TDP1 | |
| SCHEMBL3469938 | 0.70 | ALDH1A1 (0.34) | ALDH1A1TDP1 | |
| SCHEMBL2066341 | 0.69 | — | — | |
| SCHEMBL15727986 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2310053-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING A COMPLEX OF AMINOCYCLOHEXANE DERIVATIVES AND CYCLODEXTRIN | Merz Pharma GmbH & Co. KGaA (DE) | 2011-04-20 | — | — | EP | disclosed |
| EP-2200600-A1 | 1-AMINO-ALKYLCYCLOHEXANE DERIVATIVES FOR THE TREATMENT OF COCHLEAR TINNITUS | Merz Pharma GmbH & Co. KGaA (DE) | 2010-06-30 | — | — | EP | disclosed |
| EP-2162124-A1 | NERAMEXANE FOR THE TREATMENT OF NYSTAGMUS | Merz Pharma GmbH & Co. KGaA (DE) | 2010-03-17 | — | — | EP | disclosed |
| WO-2009156160-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING A COMPLEX OF AMINOCYCLOHEXANE DERIVATIVES AND CYCLODEXTRIN | MERZ PHARMA GMBH & CO. KGAA (DE) | 2009-12-30 | — | — | WO | disclosed |
| WO-2009033652-A1 | 1-AMINO-ALKYLCYCLOHEXANE DERIVATIVES FOR THE TREATMENT OF COCHLEAR TINNITUS | MERZ PHARMA GMBH & CO. KGAA (DE) | 2009-03-19 | — | — | WO | disclosed |
| WO-2008148564-A1 | NERAMEXANE FOR THE TREATMENT OF NYSTAGMUS | MERZ PHARMA GMBH & CO. KGAA (DE) | 2008-12-11 | — | — | WO | disclosed |