SCHEMBL16919862

SCHEMBL16919862

Cc1ccc2sc3ncncc3c2c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.39
ICAM1 P05362 1/20 0.34
SELE P16581 1/20 0.34
VCAM1 P19320 1/20 0.34
CLK1 P49759 1/20 0.33
EGFR P00533 1/20 0.32
FGFR1 P11362 1/20 0.32
SRC P12931 1/20 0.32
IKBKB O14920 1/20 0.32
KDM4E B2RXH2 1/20 0.32
PIM1 P11309 1/20 0.32
PIM2 Q9P1W9 1/20 0.32
IDO1 P14902 1/20 0.31
PIP4K2A P48426 1/20 0.31
PIP4K2C Q8TBX8 1/20 0.31
RIPK2 O43353 1/20 0.31
MAPT P10636 1/20 0.31
RAB9A P51151 1/20 0.31
FDPS P14324 2/20 0.31
GABRP O00591 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16919859 0.87 BCL2L1 (0.36) ACHEICAM1SELEVCAM1CLK1
SCHEMBL14232403 0.81 IKBKB (0.44) ACHECLK1EGFRFGFR1SRC
SCHEMBL22249793 0.80 ROCK1 (0.41) CLK1KDM4EPIM1PIM2IDO1
SCHEMBL25662794 0.77 IKBKB (0.44) ICAM1SELEVCAM1CLK1IKBKB
SCHEMBL16922437 0.77 EGFR (0.38) ACHEICAM1SELEVCAM1CLK1
SCHEMBL19052485 0.75 IKBKB (0.34) ACHECLK1EGFRFGFR1SRC
SCHEMBL24270404 0.75 CYP2A6 (0.34) EGFR
SCHEMBL3038100 0.75 GPR3 (0.48) EGFRKDM4EMAPTRAB9AGABRP
SCHEMBL29717311 0.75 GPR3 (0.48) EGFRKDM4EMAPTRAB9AGABRP
SCHEMBL16283919 0.75 ATM (0.44) CLK1IKBKBPIP4K2APIP4K2CRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230172057-A1 HETEROCYCLIC COMPOUND CONTAINING HETEROATOM SUBSTITUTED FLUORENE AND OPTOELECTRONIC DEVICE WUHAN TIANMA MICRO-ELECTRONICS CO., LTD. (CN) 2023-06-01 US disclosed
EP-2910555-B1 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORP (US) 2019-03-27 EP disclosed
US-9755159-B2 Organic materials for OLEDs UNIVERSAL DISPLAY CORPORATION (US) 2017-09-05 US disclosed
US-9755159-B2 Organic materials for OLEDs UNIVERSAL DISPLAY CORPORATION (US) 2017-09-05 US disclosed
US-9502656-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2016-11-22 US disclosed
US-9502656-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2016-11-22 US disclosed
US-20150243893-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2015-08-27 US disclosed
US-20150243893-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2015-08-27 US disclosed
EP-2910555-A1 Organic electroluminescent materials and devices Universal Display Corporation (US) 2015-08-26 EP disclosed
US-20150207082-A1 ORGANIC MATERIALS FOR OLEDS UNIVERSAL DISPLAY CORPORATION (US) 2015-07-23 US disclosed
US-20150207082-A1 ORGANIC MATERIALS FOR OLEDS UNIVERSAL DISPLAY CORPORATION (US) 2015-07-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150207082-A1 ORGANIC MATERIALS FOR OLEDS OCIAD1, OCIAD2, SLC25A21 ACHE 2552/4885ICAM1 3310/4885SELE 3344/4885
US-20230172057-A1 HETEROCYCLIC COMPOUND CONTAINING HETEROATOM SUBSTITUTED FLUORENE AND OPTOELECTRONIC DEVICE CHRM1, CHRM2, CHRM4 ACHE 2213/4885ICAM1 3566/4885SELE 3874/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.