Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.95 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.95 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.66 |
| ▸ | TSHR | P16473 | 1/20 | 0.66 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.53 |
| ▸ | HRH1 | P35367 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2-Piperazin-1-Yl-Pyrimidine SCHEMBL893739 | 1.00 | ALDH1A1 (0.95) | ALDH1A1KDM4ECYP2D6CYP3A4TSHR | |
| 2-Piperazin-1-Yl-Pyrimidine SCHEMBL27920766 | 0.98 | ALDH1A1 (0.91) | ALDH1A1KDM4ECYP2D6CYP3A4TSHR | |
| 2-Piperazin-1-Yl-Pyrimidine SCHEMBL27324991 | 0.98 | ALDH1A1 (0.91) | ALDH1A1KDM4ECYP2D6CYP3A4TSHR | |
| 2-Piperazin-1-Yl-Pyrimidine SCHEMBL101561 | 0.98 | ALDH1A1 (1.00) | ALDH1A1KDM4ECYP2D6CYP3A4TSHR | |
| 2-Piperazin-1-Yl-Pyrimidine SCHEMBL924147 | 0.98 | ALDH1A1 (1.00) | ALDH1A1KDM4ECYP2D6CYP3A4TSHR | |
| 2-Piperazin-1-Yl-Pyrimidine SCHEMBL5375472 | 0.98 | ALDH1A1 (0.91) | ALDH1A1KDM4ECYP2D6CYP3A4TSHR | |
| 2-Piperazin-1-Yl-Pyrimidine SCHEMBL6861317 | 0.96 | ALDH1A1 (0.96) | ALDH1A1KDM4ECYP2D6CYP3A4TSHR | |
| SCHEMBL1254909 | 0.92 | ALDH1A1 (0.81) | ALDH1A1KDM4ECYP2D6CYP3A4TSHR | |
| Hydrochloric Acid SCHEMBL27146448 | 0.90 | ALDH1A1 (0.85) | ALDH1A1KDM4ECYP2D6CYP3A4TSHR | |
| 2-Piperazin-1-Yl-Pyrimidine SCHEMBL28926339 | 0.88 | KDM4E (0.75) | ALDH1A1KDM4ECYP2D6CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 4670 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122055732-A | Computer-implemented method and system for operating a technical device | 西门子股份公司 | 2026-05-15 | — | — | CN | claimed |
| CN-122011028-A | Method for efficiently preparing various substituted chiral phosphoramides | 上海交通大学 | 2026-05-12 | — | — | CN | claimed |
| CN-119840052-B | Numerical control electric heating circulation vulcanizing machine for rubber and control system | 湖南斯珀特家居用品有限公司 | 2025-06-24 | — | — | CN | claimed |
| CN-119442896-B | Method and device for realizing interoperation of simulation system | 北京华如科技股份有限公司 | 2025-06-10 | — | — | CN | claimed |
| CN-120117949-A | Method for directly preparing tertiary amine compound from aromatic aldehyde, ketone and secondary amine | 湖南大学 | 2025-06-10 | — | — | CN | claimed |
| CN-119707902-B | Preparation method of daphnetin | 吉林大学第一医院 | 2025-05-30 | — | — | CN | claimed |
| CN-119840052-A | Numerical control electric heating circulation vulcanizing machine for rubber and control system | 湖南斯珀特家居用品有限公司 | 2025-04-18 | — | — | CN | claimed |
| CN-119751362-A | Method for continuously preparing 1- (2-pyrimidinyl) piperazine | 爱斯特（成都）生物制药股份有限公司 | 2025-04-04 | — | — | CN | claimed |
| CN-119707902-A | Preparation method of daphnetin | 吉林大学第一医院 | 2025-03-28 | — | — | CN | claimed |
| CN-119442896-A | Method and device for realizing interoperation of simulation system | 北京华如科技股份有限公司 | 2025-02-14 | — | — | CN | claimed |
| US-4542136-A | 2-(1-Piperazinyl) pyrimidines, their salts and pharmaceutical compositions containing them | SANOFI (FR) | 1985-09-17 | — | — | US | claimed |
| EP-0151140-A1 | 2-PIPERAZINOPYRIMIDINE SALT, PREPARATION METHOD THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING IT. | SANOFI SA (FR) | 1985-08-14 | — | — | EP | claimed |
| EP-0115496-A4 | CYANOALKYLPIPERAZINES AND METHODS FOR THEIR PREPARATION AND USE. | EASTMAN KODAK CO (US) | 1985-06-26 | — | — | EP | claimed |
| WO-1985000168-A1 | 2-PIPERAZINOPYRIMIDINE SALT, PREPARATION METHOD THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING IT | SANOFI (FR) | 1985-01-17 | — | — | WO | claimed |
| EP-0115713-A1 | 2-(1-Piperazinyl)-pyrimidines, their salts, process for their preparation and pharmaceutical compositions containing them | SANOFI S.A. (FR) | 1984-08-15 | — | — | EP | claimed |
| EP-0115496-A1 | CYANOALKYLPIPERAZINES AND METHODS FOR THEIR PREPARATION AND USE. | EASTMAN KODAK CO (US) | 1984-08-15 | — | — | EP | claimed |
| EP-0115714-A1 | Pharmaceutical composition with psychotropic dopaminergic action | SANOFI S.A. (FR) | 1984-08-15 | — | — | EP | claimed |
| EP-0109340-A2 | Acid salts of 2-piperazinopyrimidine, process for their preparation and pharmaceutical compositions containing them | SANOFI S.A. (FR) | 1984-05-23 | — | — | EP | claimed |
| WO-1984000753-A1 | CYANOALKYLPIPERAZINES AND METHODS FOR THEIR PREPARATION AND USE | EASTMAN KODAK CO (US) | 1984-03-01 | — | — | WO | claimed |
| US-4409223-A | Anxiolytic method | BRISTOL-MYERS COMPANY | 1983-10-11 | — | — | US | claimed |