⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methyl Alcohol SCHEMBL9117524 | 1.00 | TSHR (0.33) | — | |
| Methyl Alcohol SCHEMBL12474241 | 0.95 | TSHR (0.32) | — | |
| Methyl Alcohol SCHEMBL3128208 | 0.91 | TSHR (0.30) | — | |
| Isopropyl Alcohol SCHEMBL10648802 | 0.91 | ALDH1A1 (0.50) | — | |
| SCHEMBL7240952 | 0.89 | — | — | |
| SCHEMBL10940023 | 0.89 | — | — | |
| SCHEMBL1331944 | 0.89 | — | — | |
| SCHEMBL1296 | 0.89 | — | — | |
| SCHEMBL27912512 | 0.89 | MAPK1 (0.31) | — | |
| Chloroform SCHEMBL4322061 | 0.88 | ALDH1A1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 906 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116715660-A | Amorphous matter of terglazan and preparation method thereof | 上海柏狮生物科技有限公司 | 2023-09-08 | — | — | CN | claimed |
| US-20210188856-A1 | CRYSTAL FORM OF HYDROCHLORIDE OF PYRAZOLOHETEROARYL DERIVATIVE AND PREPARATION METHOD | SHANGHAI HENGRUI PHARMACEUTICAL CO., LTD (CN) | 2021-06-24 | — | — | US | claimed |
| EP-3808745-A1 | CRYSTAL FORM OF HYDROCHLORIDE OF PYRAZOLOHETEROARYL DERIVATIVE AND PREPARATION METHOD | Jiangsu Hengrui Medicine Co., Ltd. (CN) | 2021-04-21 | — | — | EP | claimed |
| CN-102249936-B | Hydrate of O-desmethylvenlafaxine hydrochloride and preparation method thereof | JIANGSU HANSOH MEDICAL GROUP CO LTD | 2014-09-17 | — | — | CN | claimed |
| US-6518456-B1 | Process for the production and purification of gabapentin, i.e. 1-(aminomethyl)cyclohexyl-acetic acid, which comprises hydrolysis of 2-aza-spiro(4.5)decan-3-one with HCl, treatment of the resulting product and filtration with | PROCOS S.P.A. (IT) | 2003-02-11 | — | — | US | claimed |
| EP-4395840-A1 | MAGL INHIBITORS | F. Hoffmann-La Roche AG (CH) | 2024-07-10 | — | — | EP | disclosed |
| CN-112469707-B | Preventive or therapeutic agent for spinal muscular atrophy | 利伯纳生物科学株式会社 | 2024-06-21 | — | — | CN | disclosed |
| US-12012410-B2 | Substituted pyrazolo[1,5-a]pyrazines for spinal muscular atrophy | REBORNA BIOSCIENCES, INC. (JP) | 2024-06-18 | — | — | US | disclosed |
| CN-117836014-A | MAGL inhibitors | 豪夫迈·罗氏有限公司 | 2024-04-05 | — | — | CN | disclosed |
| CN-116715660-A | Amorphous matter of terglazan and preparation method thereof | 上海柏狮生物科技有限公司 | 2023-09-08 | — | — | CN | disclosed |
| US-20230167096-A1 | VORUCICLIB POLYMORPHS AND METHODS OF MAKING AND USING THEREOF | MEI PHARMA, INC. (US) | 2023-06-01 | — | — | US | disclosed |
| EP-3395819-B1 | CRYSTAL FORM OF SUBSTITUTED AMINOPYRAN DERIVATIVE | SICHUAN HAISCO PHARMACEUTICAL CO LTD (CN) | 2023-05-31 | — | — | EP | disclosed |
| US-4000280-A | PHARMACEUTICAL COMPOSITIONS CONTAINING AN AMPHETAMINE DERIVATIVE FOR THE ALLEVIATION OF ANXIETY OR TREATMENT OF DEPRESSION | ASTRA LAKEMEDEL AKTIEBOLAG (SW) | 1976-12-28 | — | — | US | disclosed |
| US-3996381-A | ANTIDEPRESSANT | ASTRA LAKEMEDEL AKTIEBOLAG (SW) | 1976-12-07 | — | — | US | disclosed |
| US-3979514-A | Process for interrupting pregnancy with sulfonamidoaminophene interceptive agents | MEAD JOHNSON & COMPANY (US) | 1976-09-07 | — | — | US | disclosed |
| US-3963726-A | Quaternary ammonium salts of chloromethylated silicon compounds | UNION CARBIDE CORPORATION (US) | 1976-06-15 | — | — | US | disclosed |
| US-3956296-A | ANTIINFLAMMATORY, SEDATIVES, TRANQUILIZERS | A. H. ROBINS COMPANY, INCORPORATED (US) | 1976-05-11 | — | — | US | disclosed |
| US-3947569-A | Process for preparing the releasing hormone of luteinizing hormone (LH) and of follicle stimulating hormone (FSH), salts and compositions thereof, and intermediates therefor | AMERICAN HOME PRODUCTS CORPORATION (US) | 1976-03-30 | — | — | US | disclosed |
| US-3940354-A | BACTERICIDE | ROUSSEL-UCLAF (FR) | 1976-02-24 | — | — | US | disclosed |
| US-3931195-A | ANTIARRHYTHMIA, ANTISEROTONIN | MEAD JOHNSON & COMPANY (US) | 1976-01-06 | — | — | US | disclosed |