SCHEMBL16922467

SCHEMBL16922467

c1ccc(-c2nc(-c3ccccc3)nc(-c3cccc(-c4ccc(-c5nccc6c5oc5ccccc56)cc4)c3)n2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.39
KMT2A Q03164 4/20 0.39
MEN1 O00255 3/20 0.39
CSF1R P07333 1/20 0.39
PDGFRB P09619 1/20 0.39
KIT P10721 1/20 0.39
FLT3 P36888 1/20 0.39
HDAC6 Q9UBN7 1/20 0.39
ALDH1A1 P00352 4/20 0.39
KDM4E B2RXH2 3/20 0.39
POLB P06746 2/20 0.39
PLA2G2A P14555 2/20 0.39
PLA2G4A P47712 2/20 0.39
TSHR P16473 2/20 0.38
LMNA P02545 2/20 0.38
ALOX5 P09917 1/20 0.38
HTT P42858 1/20 0.38
ATM Q13315 2/20 0.37
HTR2B P41595 1/20 0.37
HTR5A P47898 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16922470 0.96 ALDH1A1 (0.40) MAPTKMT2AMEN1CSF1RPDGFRB
SCHEMBL16922466 0.95 ALDH1A1 (0.40) MAPTKMT2AMEN1CSF1RPDGFRB
SCHEMBL16922383 0.94 MAPT (0.40) MAPTKMT2AMEN1CSF1RPDGFRB
SCHEMBL16922561 0.90 MAPK10 (0.36) MAPTKMT2AMEN1ALDH1A1KDM4E
SCHEMBL16922577 0.89 HTR2B (0.41) MAPTKMT2AMEN1CSF1RPDGFRB
SCHEMBL25462395 0.89 KDM4E (0.37) MAPTKMT2AMEN1CSF1RPDGFRB
SCHEMBL16922554 0.89 MAPK10 (0.38) MAPTKMT2AMEN1ALDH1A1KDM4E
SCHEMBL24602261 0.87 KDM4E (0.33) MAPTKMT2AMEN1CSF1RPDGFRB
SCHEMBL24602262 0.87 KDM4E (0.33) MAPTKMT2AMEN1CSF1RPDGFRB
SCHEMBL16922565 0.87 PIK3CA (0.43) MAPTKMT2AMEN1FLT3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9755159-B2 Organic materials for OLEDs UNIVERSAL DISPLAY CORPORATION (US) 2017-09-05 US disclosed
US-20150207082-A1 ORGANIC MATERIALS FOR OLEDS UNIVERSAL DISPLAY CORPORATION (US) 2015-07-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150207082-A1 ORGANIC MATERIALS FOR OLEDS OCIAD1, OCIAD2, SLC25A21 MAPT 559/4885KMT2A 1959/4885MEN1 4395/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.