Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 3/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.31 |
| ▸ | KIF11 | P52732 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15588319 | 0.85 | PTPN2 (0.33) | KDM1AKCNH2KDM1BFFAR1FFAR4 | |
| SCHEMBL17295331 | 0.85 | MELK (0.42) | KDM1AKCNH2KDM1BFFAR1FFAR4 | |
| SCHEMBL15588338 | 0.83 | FFAR1 (0.34) | KDM1AKCNH2KDM1BFFAR1FFAR4 | |
| SCHEMBL7651081 | 0.82 | CYP2D6 (0.36) | KDM1AKCNH2KDM1BGRM5RCOR1 | |
| SCHEMBL7788815 | 0.78 | FFAR1 (0.43) | KCNH2FFAR1FFAR4GRM5 | |
| SCHEMBL19608768 | 0.78 | CYP1A1 (0.39) | KDM1AKCNH2KDM1BGRM5RCOR1 | |
| SCHEMBL27865875 | 0.78 | GRM5 (0.44) | KDM1AKCNH2KDM1BFFAR1FFAR4 | |
| SCHEMBL13564076 | 0.77 | FFAR1 (0.45) | KCNH2FFAR1FFAR4 | |
| SCHEMBL7786194 | 0.77 | FFAR1 (0.45) | KCNH2FFAR1FFAR4 | |
| SCHEMBL19374589 | 0.77 | HDAC1 (0.31) | FFAR1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9914876-B2 | Bimesogenic compounds and mesogenic media | MERCK PATENT GMBH (DE) | 2018-03-13 | — | — | US | disclosed |
| US-20150203755-A1 | BIMESOGENIC COMPOUNDS AND MESOGENIC MEDIA | MERCK PATENT GMBH (DE) | 2015-07-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150203755-A1 | BIMESOGENIC COMPOUNDS AND MESOGENIC MEDIA | SP1, FOXM1, S100A11 | KDM1A 3079/4885KCNH2 3522/4885KDM1B 2623/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.