Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.37 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.37 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15553456 | 0.99 | PDK2 (0.44) | PDK2ALDH1A1MAPK1FLT3KDM4E | |
| SCHEMBL3176035 | 0.97 | ALDH1A1 (0.41) | PDK2ALDH1A1MAPK1FLT3KDM4E | |
| SCHEMBL12781959 | 0.96 | PDK2 (0.44) | PDK2ALDH1A1MAPK1FLT3KDM4E | |
| SCHEMBL16852587 | 0.93 | PDK2 (0.44) | PDK2ALDH1A1MAPK1FLT3KDM4E | |
| SCHEMBL12781965 | 0.93 | PDK2 (0.46) | PDK2ALDH1A1MAPK1FLT3KDM4E | |
| SCHEMBL16922978 | 0.93 | MAPK1 (0.45) | PDK2ALDH1A1MAPK1KDM4EHPGD | |
| SCHEMBL16922981 | 0.90 | MAPK1 (0.45) | PDK2ALDH1A1MAPK1KDM4EHPGD | |
| SCHEMBL3852176 | 0.90 | PDK2 (0.41) | PDK2ALDH1A1MAPK1KDM4EMEN1 | |
| SCHEMBL12635475 | 0.89 | MAPK1 (0.48) | PDK2ALDH1A1MAPK1FLT3KDM4E | |
| SCHEMBL16852597 | 0.87 | PDK2 (0.44) | PDK2ALDH1A1MAPK1FLT3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11258018-B2 | Compounds and organic electronic devices | MERCK PATENT GMBH (DE) | 2022-02-22 | — | — | US | disclosed |
| US-20190348605-A1 | COMPOUNDS AND ORGANIC ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2019-11-14 | — | — | US | disclosed |
| US-20170317285-A1 | Compounds and Organic Electronic Devices | MERCK PATENT GMBH (DE) | 2017-11-02 | — | — | US | disclosed |
| US-20170317285-A1 | Compounds and Organic Electronic Devices | MERCK PATENT GMBH (DE) | 2017-11-02 | — | — | US | disclosed |
| US-9768391-B2 | Derivatives of 2-diarylaminofluorene and organic electronic compounds containing them | MERCK PATENT GMBH (DE) | 2017-09-19 | — | — | US | disclosed |
| US-9768391-B2 | Derivatives of 2-diarylaminofluorene and organic electronic compounds containing them | MERCK PATENT GMBH (DE) | 2017-09-19 | — | — | US | disclosed |
| EP-2875699-B1 | DERIVATES OF 2-DIARYLAMINOFLUOREN AND ORGANIC ELECTRONIC DEVICES COMPRISING THE SAME | MERCK PATENT GMBH (DE) | 2017-02-15 | — | — | EP | disclosed |
| US-20150207075-A1 | DERIVATIVES OF 2-DIARYLAMINOFLUORENE AND ORGANIC ELECTRONIC COMPOUNDS CONTAINING THEM | MERCK PATENT GMBH (DE) | 2015-07-23 | — | — | US | disclosed |
| US-20150207075-A1 | DERIVATIVES OF 2-DIARYLAMINOFLUORENE AND ORGANIC ELECTRONIC COMPOUNDS CONTAINING THEM | MERCK PATENT GMBH (DE) | 2015-07-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150207075-A1 | DERIVATIVES OF 2-DIARYLAMINOFLUORENE AND ORGANIC ELECTRONIC COMPOUNDS CONTAINING THEM | DDT, AFF2, CYP2F1 | PDK2 718/4885ALDH1A1 349/4885MAPK1 2110/4885 |
| US-20190348605-A1 | COMPOUNDS AND ORGANIC ELECTRONIC DEVICES | ETV6, CYP2C19, AFF2 | PDK2 1406/4885ALDH1A1 408/4885MAPK1 2317/4885 |
| US-20170317285-A1 | Compounds and Organic Electronic Devices | ETV6, CYP2C19, AFF2 | PDK2 1406/4885ALDH1A1 408/4885MAPK1 2317/4885 |
| US-11258018-B2 | Compounds and organic electronic devices | ETV6, CYP2C19, AFF2 | PDK2 1406/4885ALDH1A1 408/4885MAPK1 2317/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.