Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 3/20 | 0.49 |
| ▸ | CYCS | P99999 | 3/20 | 0.48 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.47 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.44 |
| ▸ | ATR | Q13535 | 5/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | CCNC | P24863 | 2/20 | 0.42 |
| ▸ | CDK8 | P49336 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17934755 | 0.87 | TOP1 (0.52) | TOP1CYCSMKNK2MKNK1SIGMAR1 | |
| SCHEMBL16923663 | 0.75 | TOP1 (0.52) | TOP1CYCSKDM4EHTR2B | |
| SCHEMBL16920371 | 0.73 | TOP1 (0.49) | TOP1CYCSKDM4EHTR2B | |
| SCHEMBL27814176 | 0.73 | TOP1 (0.71) | TOP1CYCSMKNK2MKNK1 | |
| SCHEMBL25395869 | 0.72 | TOP1 (0.91) | TOP1CYCSKDM4E | |
| SCHEMBL16418477 | 0.72 | TOP1 (0.91) | TOP1CYCSKDM4E | |
| SCHEMBL483511 | 0.72 | TOP1 (0.91) | TOP1CYCSKDM4E | |
| SCHEMBL25394852 | 0.72 | TOP1 (0.91) | TOP1CYCSKDM4E | |
| SCHEMBL29556585 | 0.72 | TOP1 (0.91) | TOP1CYCSKDM4E | |
| SCHEMBL17934753 | 0.72 | TOP1 (0.46) | TOP1CYCSATRHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150202293-A1 | CONJUGATE OF A PHOTOSENSITISER AND CHITOSAN AND USES THEREOF | PCI BIOTECH AS (NO) | 2015-07-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150202293-A1 | CONJUGATE OF A PHOTOSENSITISER AND CHITOSAN AND USES THEREOF | TLR3, CD47, TLR9 | TOP1 2741/4885CYCS 3103/4885MKNK2 1723/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.