SCHEMBL483511

SCHEMBL483511

O=C(O)c1ccc(-c2c3nc(c(-c4ccccc4)c4ccc([nH]4)c(-c4ccccc4)c4nc(c(-c5ccccc5)c5ccc2[nH]5)C=C4)C=C3)cc1

nearest known ligand 0.91

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ TOP1 P11387 4/20 0.91
▸ CYCS P99999 4/20 0.88
▸ ENPP2 Q13822 1/20 0.55
▸ ABCG2 Q9UNQ0 1/20 0.51
▸ STAT3 P40763 1/20 0.50
▸ STAT1 P42224 1/20 0.50
▸ KDM4E B2RXH2 2/20 0.48
▸ ALDH1A1 P00352 2/20 0.48
▸ HPGD P15428 2/20 0.48
▸ KMT2A Q03164 2/20 0.48
▸ GLA P06280 1/20 0.48
▸ GAA P10253 1/20 0.48
▸ TERT O14746 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29556585 1.00 TOP1 (0.91) TOP1CYCSENPP2ABCG2STAT3
SCHEMBL25395869 1.00 TOP1 (0.91) TOP1CYCSENPP2ABCG2STAT3
SCHEMBL16418477 1.00 TOP1 (0.91) TOP1CYCSENPP2ABCG2STAT3
SCHEMBL25394852 1.00 TOP1 (0.91) TOP1CYCSENPP2ABCG2STAT3
SCHEMBL29520928 0.98 TOP1 (0.88) TOP1CYCSENPP2ABCG2STAT3
SCHEMBL19640818 0.98 CYCS (0.91) TOP1CYCSENPP2ABCG2STAT3
SCHEMBL6693557 0.98 TOP1 (0.88) TOP1CYCSENPP2ABCG2STAT3
SCHEMBL6686149 0.98 TOP1 (0.88) TOP1CYCSENPP2ABCG2STAT3
SCHEMBL29354037 0.95 TOP1 (1.00) TOP1CYCSENPP2ABCG2KDM4E
SCHEMBL709532 0.95 TOP1 (1.00) TOP1CYCSENPP2ABCG2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117482993-A Method for preparing hydrogen peroxide based on amorphous porphyrin supermolecule photocatalyst 江南大学 2024-02-02 — — CN claimed
CN-114716446-B Preparation method of amino acid porphyrin with enhanced aggregation-induced fluorescence 井冈山大学 2023-03-17 — — CN claimed
CN-113218921-B Fluorescence ratio sensor for detecting heavy metals 江门职业技术学院 2022-08-12 — — CN claimed
CN-114716446-A Preparation method of amino acid porphyrin with enhanced aggregation-induced fluorescence 井冈山大学 2022-07-08 — — CN claimed
CN-112940268-B Interface in-situ growth metal-organic framework material and preparation method and application thereof 中国科学院宁波材料技术与工程研究所 2022-04-12 — — CN claimed
CN-113218921-A Fluorescence ratio sensor for detecting heavy metals 江门职业技术学院 2021-08-06 — — CN claimed
CN-113109304-A Recyclable and reusable fluorescent sensor and preparation method thereof 江门职业技术学院 2021-07-13 — — CN claimed
CN-113092423-A Solid-state fluorescence sensor, preparation method thereof and application thereof in metal ion detection 江门职业技术学院 2021-07-09 — — CN claimed
CN-112940268-A Interface in-situ growth metal-organic framework material and preparation method and application thereof 中国科学院宁波材料技术与工程研究所 2021-06-11 — — CN claimed
CN-110041339-B Benzimidazolyl zinc porphyrin, benzimidazolyl porphyrin and synthesis method thereof 廊坊师范学院 2021-02-02 — — CN claimed
US-9581594-B2 Porphyrin—modified antimicrobial peptides for application as indicators of microbial targets THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2017-02-28 — — US claimed
CN-104127882-B The super-molecule assembling body of a kind of targeted delivery paclitaxel anticancer prodrug and preparation method 南开大学 2016-07-20 — — CN claimed
CN-104127882-A Supermolecular assembly for targeted conduction of anticancer taxol prodrug and preparation method thereof UNIV NANKAI 2014-11-05 — — CN claimed
WO-2014159904-A1 PORPHYRIN-MODIFIED ANTIMICROBIAL PEPTIDES FOR APPLICATION AS INDICATORS OF MICROBIAL TARGETS THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2014-10-02 — — WO claimed
US-20140274776-A1 Porphyrin-Modified Antimicrobial Peptides for Application as Indicators of Microbial Targets THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2014-09-18 — — US claimed
CN-102258788-B Targeted transmission assembly of adriamycin anticancer medicine and preparation method thereof UNIV NANKAI 2012-11-07 — — CN claimed
CN-102258788-A Targeted transmission assembly of adriamycin anticancer medicine and preparation method thereof — 2011-11-30 — — CN claimed
US-20250034027-A1 METHOD FOR PREPARING GLASS NANOSTRUCTURES AND NANOSTRUCTURED SUBSTRATES THEREOF CORNING INCORPORATED 2025-01-30 — — US disclosed
US-4614723-A Porphyrin derivatives as fluorescent markers for immunoassays HOFFMANN-LA ROCHE INC. (US) 1986-09-30 — — US disclosed
EP-0127797-A1 Labelled molecules for fluorescence immunoassays and processes and intermediates for their preparation F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1984-12-12 — — EP disclosed
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