Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 3/20 | 0.42 |
| ▸ | THRB | P10828 | 3/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | EIF4E | P06730 | 5/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.38 |
| ▸ | USP10 | Q14694 | 1/20 | 0.38 |
| ▸ | USP7 | Q93009 | 1/20 | 0.38 |
| ▸ | USP47 | Q96K76 | 1/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.37 |
| ▸ | EP300 | Q09472 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31341303 | 0.81 | HDAC1 (0.45) | PPARGEIF4ENOTUMHDAC3HDAC4 | |
| SCHEMBL31341240 | 0.79 | EIF4E (0.42) | PPARGEIF4ENOTUMHDAC3HDAC4 | |
| SCHEMBL16703315 | 0.78 | HDAC1 (0.54) | NOTUMHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL31341341 | 0.76 | MAPT (0.40) | NOTUMHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL16923859 | 0.75 | TDP1 (0.43) | ATMTDP1EIF4ECASP6 | |
| SCHEMBL16703334 | 0.71 | PTPN11 (0.59) | PPARGHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL971661 | 0.70 | TDP1 (0.46) | THRBATMTDP1EIF4EUSP10 | |
| SCHEMBL6662966 | 0.70 | HDAC1 (0.49) | PPARGNOTUMHDAC1HDAC6HCAR2 | |
| SCHEMBL16703124 | 0.70 | CSNK1D (0.53) | HDAC1HDAC6 | |
| SCHEMBL27935663 | 0.70 | XDH (0.56) | PPARGTDP1HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015108038-A1 | ETHYLENE GLYCOL COMPOUND | 第一三共株式会社 | 2015-07-23 | — | — | WO | disclosed |