Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAOK3 | Q9H2K8 | 2/20 | 0.49 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | CTSS | P25774 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.41 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL40139 | 0.87 | POLB (0.53) | TAOK3TAOK1POLBMEN1KMT2A | |
| SCHEMBL16924178 | 0.86 | TAS1R3 (0.52) | POLBMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL16923867 | 0.85 | MEN1 (0.51) | TAOK3TAOK1POLBMEN1KMT2A | |
| SCHEMBL16923851 | 0.84 | KMT2A (0.52) | POLBMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL16924078 | 0.82 | POLB (0.49) | TAOK3TAOK1POLBMEN1KMT2A | |
| SCHEMBL16923911 | 0.81 | POLB (0.51) | TAOK3TAOK1POLBMEN1KMT2A | |
| SCHEMBL16924093 | 0.81 | POLB (0.50) | TAOK3TAOK1POLBMEN1KMT2A | |
| SCHEMBL16923965 | 0.81 | TAOK1 (0.47) | TAOK3TAOK1POLBMEN1KMT2A | |
| SCHEMBL16923861 | 0.81 | TAOK3 (0.47) | TAOK3TAOK1POLBMEN1KMT2A | |
| SCHEMBL16924086 | 0.80 | MEN1 (0.49) | TAOK3TAOK1POLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015108038-A1 | ETHYLENE GLYCOL COMPOUND | 第一三共株式会社 | 2015-07-23 | — | — | WO | disclosed |