Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH2 | P05091 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | NCOA2 | Q15596 | 2/20 | 0.41 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16925924 | 0.93 | ALDH2 (0.49) | ALDH2KDM4EL3MBTL1ATMNPSR1 | |
| SCHEMBL16925779 | 0.92 | KDM4E (0.51) | ALDH2KDM4EL3MBTL1ATMNPSR1 | |
| SCHEMBL16925933 | 0.91 | KDM4E (0.45) | ALDH2KDM4EL3MBTL1ATMNPSR1 | |
| SCHEMBL16925930 | 0.91 | KDM4E (0.45) | ALDH2KDM4EL3MBTL1ATMNPSR1 | |
| SCHEMBL16925927 | 0.91 | ALDH2 (0.43) | ALDH2KDM4EL3MBTL1ATMNPSR1 | |
| SCHEMBL16925932 | 0.90 | KDM4E (0.46) | ALDH2KDM4EL3MBTL1ATMNPSR1 | |
| SCHEMBL23058484 | 0.88 | L3MBTL1 (0.53) | KDM4EL3MBTL1ATMLMNAKMT2A | |
| SCHEMBL16925864 | 0.87 | ALDH2 (0.46) | ALDH2KDM4EL3MBTL1ATMNPSR1 | |
| SCHEMBL16925677 | 0.87 | KDM4E (0.51) | ALDH2KDM4EL3MBTL1ATMNPSR1 | |
| SCHEMBL16925905 | 0.86 | KDM4E (0.45) | ALDH2KDM4EL3MBTL1ATMNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10000694-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2018-06-19 | — | — | US | disclosed |
| US-10000694-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2018-06-19 | — | — | US | disclosed |
| EP-3094703-B1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2018-02-07 | — | — | EP | disclosed |
| US-20160326429-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2016-11-10 | — | — | US | disclosed |
| WO-2015106789-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2015-07-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10000694-B2 | Materials for organic electroluminescent devices | OR10J3, EPCAM, L1CAM | ALDH2 255/4885KDM4E 1844/4885L3MBTL1 1317/4885 |
| US-20160326429-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | OR10J3, EPCAM, L1CAM | ALDH2 255/4885KDM4E 1844/4885L3MBTL1 1317/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.