SCHEMBL16928596

SCHEMBL16928596

COc1ccc(Br)cc1C=CC(=O)c1ccccc1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MAOB P27338 5/20 1.00
AR P10275 5/20 0.73
ACHE P22303 1/20 0.63
ABCG2 Q9UNQ0 1/20 0.63
MAOA P21397 1/20 0.62
TNFRSF1A P19438 1/20 0.62
NR1H4 Q96RI1 3/20 0.60
MAPT P10636 2/20 0.60
ALDH1A1 P00352 1/20 0.60
LMNA P02545 1/20 0.60
PTGS1 P23219 1/20 0.60
PTGS2 P35354 1/20 0.60
SMN1; SMN2 Q16637 1/20 0.59
PTPN1 P18031 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15630203 1.00 MAOB (1.00) MAOBARACHEABCG2MAOA
SCHEMBL15619197 0.86 MAOB (0.76) MAOBARACHEABCG2MAOA
SCHEMBL15619198 0.86 MAOB (0.76) MAOBARACHEABCG2MAOA
SCHEMBL15619317 0.86 MAOB (0.75) MAOBARACHEABCG2NR1H4
SCHEMBL5137641 0.86 MAOB (0.75) MAOBARACHEABCG2MAOA
SCHEMBL15619316 0.86 MAOB (0.75) MAOBARACHEABCG2NR1H4
SCHEMBL5137643 0.86 MAOB (0.75) MAOBARACHEABCG2MAOA
SCHEMBL15630178 0.85 MAOB (0.74) MAOBARACHEABCG2MAOA
SCHEMBL16928595 0.85 MAOB (0.74) MAOBARACHEABCG2MAOA
SCHEMBL15620265 0.85 MAOB (0.73) MAOBARACHEABCG2MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9629822-B2 Flavonoid based antiviral targets UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (US) 2017-04-25 US disclosed
US-20150209323-A1 FLAVONOID BASED ANTIVIRAL TARGETS UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, (US) 2015-07-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150209323-A1 FLAVONOID BASED ANTIVIRAL TARGETS RBM28, MAVS, HAVCR2 MAOB 4153/4885AR 4201/4885ACHE 4849/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.