Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.65 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.64 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.64 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.64 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.60 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.59 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | RXRA | P19793 | 1/20 | 0.55 |
| ▸ | RXRB | P28702 | 1/20 | 0.55 |
| ▸ | EGFR | P00533 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | LTA4H | P09960 | 1/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6816962 | 0.88 | MAOB (0.69) | MAOBNR4A1NR4A2NR4A3PARP10 | |
| SCHEMBL5078379 | 0.85 | MAOB (0.65) | MAOBNR4A1NR4A2NR4A3PARP10 | |
| SCHEMBL103047 | 0.85 | MAOB (0.65) | MAOBNR4A1NR4A2NR4A3PARP10 | |
| Hydrochloric Acid SCHEMBL9641061 | 0.84 | MAOB (0.63) | MAOBNR4A1NR4A2NR4A3PARP10 | |
| SCHEMBL13110201 | 0.84 | MAOB (0.63) | MAOBNR4A1NR4A2NR4A3PARP10 | |
| SCHEMBL10844954 | 0.83 | NR4A1 (0.70) | MAOBNR4A1NR4A2NR4A3PARP10 | |
| SCHEMBL6803381 | 0.82 | MAOB (0.61) | MAOBNR4A1NR4A2NR4A3PARP10 | |
| SCHEMBL10845248 | 0.81 | NR4A1 (0.68) | MAOBNR4A1NR4A2NR4A3PARP10 | |
| SCHEMBL3395533 | 0.81 | NR4A1 (0.68) | MAOBNR4A1NR4A2NR4A3PARP10 | |
| SCHEMBL11441298 | 0.81 | MAOB (0.60) | MAOBNR4A1NR4A2NR4A3PARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2118058-B9 | METHOD FOR THE PREPARATION OF 5-BENZYLOXY-2-(4-BENZYLOXPHENYL)-3-METHYL-1H-INDOLE | ZENTIVA KS (CZ) | 2012-03-28 | — | — | EP | disclosed |
| EP-2426105-A1 | Process for the preparation of 5-benzyloxy-2-(4-benzyloxyphenyl)-3-methyl-1h-indole | Divi's Laboratories Limited (IN) | 2012-03-07 | — | — | EP | disclosed |
| EP-2118058-B1 | METHOD FOR THE PREPARATION OF 5-BENZYLOXY-2-(4-BENZYLOXPHENYL)-3-METHYL-1H-INDOLE | ZENTIVA KS (CZ) | 2011-06-08 | — | — | EP | disclosed |