Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.63 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.62 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.62 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.62 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.59 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.57 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | RXRA | P19793 | 1/20 | 0.54 |
| ▸ | RXRB | P28702 | 1/20 | 0.54 |
| ▸ | EGFR | P00533 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | LTA4H | P09960 | 1/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.52 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6803381 | 0.87 | MAOB (0.61) | MAOBNR4A1NR4A2NR4A3PARP10 | |
| SCHEMBL6816962 | 0.86 | MAOB (0.69) | MAOBNR4A1NR4A2NR4A3PARP10 | |
| Hydrochloric Acid SCHEMBL8599010 | 0.85 | MAOB (0.58) | MAOBNR4A1NR4A2NR4A3PARP10 | |
| SCHEMBL169289 | 0.84 | MAOB (0.65) | MAOBNR4A1NR4A2NR4A3PARP10 | |
| SCHEMBL103047 | 0.84 | MAOB (0.65) | MAOBNR4A1NR4A2NR4A3PARP10 | |
| SCHEMBL5078379 | 0.84 | MAOB (0.65) | MAOBNR4A1NR4A2NR4A3PARP10 | |
| SCHEMBL9771515 | 0.83 | MAOB (0.57) | MAOBNR4A1NR4A2NR4A3PARP10 | |
| SCHEMBL8594326 | 0.83 | MAOB (0.57) | MAOBNR4A1NR4A2NR4A3PARP10 | |
| SCHEMBL11496897 | 0.82 | L3MBTL1 (0.59) | MAOBNR4A1NR4A2NR4A3PARP10 | |
| Hydrochloric Acid SCHEMBL9641061 | 0.82 | MAOB (0.63) | MAOBNR4A1NR4A2NR4A3PARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7820703-B2 | Lysophosphatidic acid receptor selective antagonists | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2010-10-26 | — | — | US | disclosed |
| US-20080318901-A1 | Novel Lysophosphatidic Acid Receptor Selective Antagonists | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2008-12-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080318901-A1 | Novel Lysophosphatidic Acid Receptor Selective Antagonists | LPAR3, LPAR2, LPAR1 | MAOB 2557/4885NR4A1 2318/4885NR4A2 1909/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.