Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | GCGR | P47871 | 3/20 | 0.35 |
| ▸ | KIF11 | P52732 | 2/20 | 0.35 |
| ▸ | IDH1 | O75874 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | ESRRA | P11474 | 2/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16929714 | 0.90 | EPHX2 (0.40) | EPHX2PPARGHDAC2S1PR1MAPK1 | |
| SCHEMBL16929723 | 0.89 | CYP11B1 (0.43) | EPHX2PPARGHDAC2MAPK1MAOA | |
| SCHEMBL16929770 | 0.88 | EPHX2 (0.43) | EPHX2PPARGHDAC2MAPK1MAOA | |
| SCHEMBL16929744 | 0.86 | FGFR1 (0.40) | EPHX2PPARGMAPK1KIF11IDH1 | |
| SCHEMBL16929777 | 0.86 | MAPK1 (0.37) | EPHX2PPARGHDAC2MAPK1MAOA | |
| SCHEMBL16929801 | 0.86 | MAOA (0.41) | EPHX2PPARGHDAC2MAPK1MAOA | |
| SCHEMBL19512140 | 0.84 | ESRRA (0.38) | EPHX2PPARGS1PR1MAPK1ESRRA | |
| SCHEMBL15076250 | 0.81 | PTGER1 (0.41) | EPHX2PPARGHDAC2 | |
| SCHEMBL23467033 | 0.81 | MAOA (0.46) | MAPK1CYP17A1CYP3A4MAOAMAOB | |
| SCHEMBL15076184 | 0.81 | EPHX2 (0.44) | EPHX2PPARGHDAC2MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9657018-B2 | Antagonists acting at multiple prostaglandin receptors for the treatment of inflammation | ALLERGAN, INC. (US) | 2017-05-23 | — | — | US | claimed |
| US-20170096423-A1 | ANTAGONISTS ACTING AT MULTIPLE PROSTAGLANDIN RECEPTORS FOR THE TREATMENT OF INFLAMMATION | ALLERGAN, INC. | 2017-04-06 | — | — | US | claimed |
| EP-3099667-B1 | ANTAGONISTS ACTING AT MULTIPLE PROSTAGLANDIN RECEPTORS FOR THE TREATMENT OF INFLAMMATION | ALLERGAN INC (US) | 2017-11-01 | — | — | EP | disclosed |
| EP-3099667-B1 | ANTAGONISTS ACTING AT MULTIPLE PROSTAGLANDIN RECEPTORS FOR THE TREATMENT OF INFLAMMATION | ALLERGAN INC (US) | 2017-11-01 | — | — | EP | disclosed |
| US-9657018-B2 | Antagonists acting at multiple prostaglandin receptors for the treatment of inflammation | ALLERGAN, INC. (US) | 2017-05-23 | — | — | US | disclosed |
| US-9657018-B2 | Antagonists acting at multiple prostaglandin receptors for the treatment of inflammation | ALLERGAN, INC. (US) | 2017-05-23 | — | — | US | disclosed |
| US-9657018-B2 | Antagonists acting at multiple prostaglandin receptors for the treatment of inflammation | ALLERGAN, INC. (US) | 2017-05-23 | — | — | US | disclosed |
| US-20170096423-A1 | ANTAGONISTS ACTING AT MULTIPLE PROSTAGLANDIN RECEPTORS FOR THE TREATMENT OF INFLAMMATION | ALLERGAN, INC. | 2017-04-06 | — | — | US | disclosed |
| US-20170096423-A1 | ANTAGONISTS ACTING AT MULTIPLE PROSTAGLANDIN RECEPTORS FOR THE TREATMENT OF INFLAMMATION | ALLERGAN, INC. | 2017-04-06 | — | — | US | disclosed |
| US-20170096423-A1 | ANTAGONISTS ACTING AT MULTIPLE PROSTAGLANDIN RECEPTORS FOR THE TREATMENT OF INFLAMMATION | ALLERGAN, INC. | 2017-04-06 | — | — | US | disclosed |
| EP-3099667-A1 | ANTAGONISTS ACTING AT MULTIPLE PROSTAGLANDIN RECEPTORS FOR THE TREATMENT OF INFLAMMATION | ALLERGAN, INC. (US) | 2016-12-07 | — | — | EP | disclosed |
| US-9365569-B2 | Antagonists acting at multiple prostaglandin receptors for the treatment of inflammation | ALLERGAN, INC. (US) | 2016-06-14 | — | — | US | disclosed |
| US-9365569-B2 | Antagonists acting at multiple prostaglandin receptors for the treatment of inflammation | ALLERGAN, INC. (US) | 2016-06-14 | — | — | US | disclosed |
| US-9365569-B2 | Antagonists acting at multiple prostaglandin receptors for the treatment of inflammation | ALLERGAN, INC. (US) | 2016-06-14 | — | — | US | disclosed |
| US-20150210689-A1 | ANTAGONISTS ACTING AT MULTIPLE PROSTAGLANDIN RECEPTORS FOR THE TREATMENT OF INFLAMMATION | ALLERGAN, INC. | 2015-07-30 | — | — | US | disclosed |
| US-20150210689-A1 | ANTAGONISTS ACTING AT MULTIPLE PROSTAGLANDIN RECEPTORS FOR THE TREATMENT OF INFLAMMATION | ALLERGAN, INC. | 2015-07-30 | — | — | US | disclosed |
| US-20150210689-A1 | ANTAGONISTS ACTING AT MULTIPLE PROSTAGLANDIN RECEPTORS FOR THE TREATMENT OF INFLAMMATION | ALLERGAN, INC. | 2015-07-30 | — | — | US | disclosed |
| WO-2015113057-A1 | ANTAGONISTS ACTING AT MULTIPLE PROSTAGLANDIN RECEPTORS FOR THE TREATMENT OF INFLAMMATION | ALLERGAN, INC. (US) | 2015-07-30 | — | — | WO | disclosed |
| WO-2015113057-A1 | ANTAGONISTS ACTING AT MULTIPLE PROSTAGLANDIN RECEPTORS FOR THE TREATMENT OF INFLAMMATION | ALLERGAN, INC. (US) | 2015-07-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150210689-A1 | ANTAGONISTS ACTING AT MULTIPLE PROSTAGLANDIN RECEPTORS FOR THE TREATMENT OF INFLAMMATION | PTGER1, PTGER4, PTGER2 | EPHX2 737/4885PPARG 36/4885HDAC2 2787/4885 |
| US-20170096423-A1 | ANTAGONISTS ACTING AT MULTIPLE PROSTAGLANDIN RECEPTORS FOR THE TREATMENT OF INFLAMMATION | PTGER1, PTGER4, PTGER2 | EPHX2 737/4885PPARG 36/4885HDAC2 2787/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.