Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10595695 | 0.79 | GAA (0.77) | GAAMAPTKDM4EGLACYP1A2 | |
| SCHEMBL11382565 | 0.76 | GAA (0.78) | GAAMAPTKDM4EGLACYP1A2 | |
| SCHEMBL537958 | 0.75 | KDM4E (0.69) | GAAMAPTKDM4EGLACYP1A2 | |
| SCHEMBL18000055 | 0.74 | KDM4E (0.68) | GAAMAPTKDM4EGLACYP1A2 | |
| SCHEMBL4447238 | 0.74 | KDM4E (0.68) | GAAMAPTKDM4EGLACYP1A2 | |
| Magnesium SCHEMBL29732237 | 0.74 | KDM4E (0.68) | GAAMAPTKDM4EGLACYP1A2 | |
| SCHEMBL8651089 | 0.74 | KDM4E (0.68) | GAAMAPTKDM4EGLACYP1A2 | |
| SCHEMBL6669513 | 0.73 | GAA (0.74) | GAAMAPTKDM4EGLACYP1A2 | |
| SCHEMBL3135935 | 0.73 | GAA (0.63) | GAAMAPTKDM4EGLACYP1A2 | |
| SCHEMBL28880300 | 0.73 | TSHR (0.81) | GAAMAPTKDM4EALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015110949-A1 | IMATINIB AS CHOLESTEROL DECREASING AGENT | NOVARTIS AG (CH) | 2015-07-30 | — | — | WO | disclosed |