SCHEMBL16939655

SCHEMBL16939655

O=C1c2ccc3c(c2C(=O)c2c1ccc1c2CCCC1)CCCC3

nearest known ligand 0.62

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CES1 P23141 8/20 0.62
PARP1 P09874 1/20 0.55
CYP19A1 P11511 2/20 0.42
BCL2L1 Q07817 1/20 0.36
BAD Q92934 1/20 0.36
HIF1A Q16665 1/20 0.35
EPAS1 Q99814 1/20 0.35
DRD2 P14416 1/20 0.35
TDP2 O95551 1/20 0.34
NSD2 O96028 1/20 0.34
HSP90AA1 P07900 1/20 0.34
PAX8 Q06710 1/20 0.34
CDC25B P30305 1/20 0.34
NOS3 P29474 1/20 0.34
NOS1 P29475 1/20 0.34
NOS2 P35228 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29505881 0.89 CES1 (0.55) CES1PARP1CDC25B
SCHEMBL57012 0.89 CES1 (0.55) CES1PARP1CDC25B
SCHEMBL29749956 0.89 CES1 (0.55) CES1PARP1CDC25B
SCHEMBL16939656 0.89 CES1 (0.55) CES1PARP1CYP19A1CDC25B
Water SCHEMBL11224287 0.87 CES1 (0.54) CES1PARP1CDC25B
SCHEMBL9149950 0.83 CES1 (0.50) CES1PARP1
SCHEMBL3328958 0.77 CES1 (0.59) CES1PARP1CYP19A1BCL2L1BAD
SCHEMBL4283299 0.76 ALDH1A1 (0.47) CES1CDC25B
SCHEMBL15866386 0.75 PARP1 (0.50) CES1PARP1CYP19A1BCL2L1BAD
SCHEMBL16023774 0.73 EED (0.66) CES1HIF1AEPAS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9139777-B2 Composition of liquid crystal medium SHENZHEN CHINA STAR OPTOELECTRONICS TECHNOLOGY CO., LTD (CN) 2015-09-22 US disclosed
US-20150210922-A1 COMPOSITION OF LIQUID CRYSTAL MEDIUM SHENZHEN CHINA STAR OPTOELECTRONICS TECHNOLOGY CO., LTD. (CN) 2015-07-30 US disclosed