Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.46 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | RAD52 | P43351 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TOP2A | P11388 | 6/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15449640 | 0.85 | POLB (0.49) | POLBL3MBTL1KMT2ANPC1MITF | |
| SCHEMBL15440469 | 0.83 | SMN1; SMN2 (0.47) | POLBL3MBTL1KMT2ANPC1MITF | |
| SCHEMBL15440739 | 0.82 | RAB9A (0.50) | POLBL3MBTL1KMT2ANPC1MITF | |
| SCHEMBL15440705 | 0.82 | POLB (0.57) | POLBL3MBTL1KMT2ANPC1MITF | |
| SCHEMBL15440679 | 0.82 | POLB (0.47) | POLBL3MBTL1KMT2ANPC1MITF | |
| SCHEMBL16945813 | 0.82 | KMT2A (0.47) | POLBL3MBTL1KMT2ANPC1MITF | |
| SCHEMBL13468463 | 0.82 | SMN1; SMN2 (0.46) | POLBL3MBTL1KMT2ANPC1MITF | |
| SCHEMBL15440706 | 0.82 | KMT2A (0.46) | POLBL3MBTL1KMT2ANPC1MITF | |
| SCHEMBL13468116 | 0.82 | SMN1; SMN2 (0.46) | POLBL3MBTL1KMT2ANPC1MITF | |
| SCHEMBL13281984 | 0.81 | SMN1; SMN2 (0.42) | POLBL3MBTL1KMT2ANPC1MITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9096536-B2 | Asymmetrically substituted anthrapyridazone derivatives as cytostatics | BS-154 S.P. ZO.O. (PL) | 2015-08-04 | — | — | US | disclosed |