⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL335804 | 0.96 | TSHR (0.57) | — | |
| SCHEMBL4514648 | 0.96 | TSHR (0.57) | — | |
| SCHEMBL1784070 | 0.96 | — | — | |
| SCHEMBL19385435 | 0.96 | TSHR (0.57) | — | |
| SCHEMBL4517239 | 0.96 | TSHR (0.57) | — | |
| SCHEMBL597810 | 0.96 | — | — | |
| SCHEMBL4219652 | 0.96 | TSHR (0.57) | — | |
| SCHEMBL592867 | 0.96 | TSHR (0.57) | — | |
| SCHEMBL8139520 | 0.96 | TSHR (0.57) | — | |
| SCHEMBL11694103 | 0.96 | TSHR (0.57) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1050 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119798181-A | (R) -4-isopropyl-3- ((R) -2-methyl-5-hexenoyl) oxazolidin-2-one and application thereof in synthesis of inchworm sex pheromone component of Western iron yew | 山东省农业科学院 | 2025-04-11 | — | — | CN | claimed |
| CN-118772194-A | Alkyl germanium compound, preparation method and application | 宝鸡文理学院 | 2024-10-15 | — | — | CN | claimed |
| CN-111393265-B | Synthesis method of 3, 5-dihydroxybenzene | 安徽中羰碳一工业技术有限责任公司 | 2024-08-02 | — | — | CN | claimed |
| CN-117945858-A | Synthesis method of cannabidiol, intermediate and preparation method thereof | 南京派康医疗科技有限公司 | 2024-04-30 | — | — | CN | claimed |
| CN-114276222-B | Diaryl benzyl alcohol compound as polypeptide liquid phase synthesis carrier and preparation method and application thereof | 杭州澳赛诺生物科技有限公司 | 2024-04-09 | — | — | CN | claimed |
| CN-116903552-A | Chiral alpha-amino alcohol compound and preparation method and application thereof | 上海大学 | 2023-10-20 | — | — | CN | claimed |
| WO-2023184731-A1 | PREPARATION METHOD FOR 4- 10 BORIC ACID-L-PHENYLALANINE INTERMEDIATE | 海南普利制药股份有限公司 | 2023-10-05 | — | — | WO | claimed |
| CN-116768733-A | Aryl cyclic ammonium salt arylation and silicon-based method | 中国科学技术大学 | 2023-09-19 | — | — | CN | claimed |
| CN-114835755-B | Catalyst of metal complex of biphosphinamide in catalytic polymerization, and preparation method | 常州德能新材料有限公司 | 2023-08-18 | — | — | CN | claimed |
| CN-116283708-A | Heptamethine cyanine iron death inducer, synthesis and application thereof | 中国人民解放军陆军军医大学 | 2023-06-23 | — | — | CN | claimed |
| CN-1142140-C | Acylation method | ������ҩ������˾ | 2004-03-17 | — | — | CN | claimed |
| EP-1088817-B1 | Process for the preparation of 3-acyl-indoles | PFIZER LTD (GB) | 2003-02-26 | — | — | EP | claimed |
| US-20020188138-A1 | Acylation process | PFIZER INC. | 2002-12-12 | — | — | US | claimed |
| US-6441192-B1 | ADDING ACID CHLORIDE AND ALKYL OR ARYL MAGNESIUM HALIDE SEPARATELY AND SIMULTANEOUSLY TO A STIRRED SOLUTION OF AN INDOLE SUCH THAT THE TWO REAGENTS DO NOT COME INTO IMMEDIATE CONTACT; SYNCHRONISED RATES OF MOLAR ADDITION | PFIZER INC. | 2002-08-27 | — | — | US | claimed |
| CN-1290697-A | Acylation method | PFIZER (US) | 2001-04-11 | — | — | CN | claimed |
| EP-1088817-A2 | Process for the preparation of 3-acyl-indoles | Pfizer Limited (GB) | 2001-04-04 | — | — | EP | claimed |
| US-5623087-A | Method for preparation of optically active diarylalanines | NDSU-RESEARCH FOUNDATION (US) | 1997-04-22 | — | — | US | claimed |
| EP-0558656-A1 | NEW METHODS FOR THE CATALYTIC REDUCTION OF ORGANIC SUBSTRATES. | MASSACHUSETTS INST TECHNOLOGY (US) | 1993-09-08 | — | — | EP | claimed |
| WO-1992009545-A2 | NEW METHODS FOR THE CATALYTIC REDUCTION OF ORGANIC SUBSTRATES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1992-06-11 | — | — | WO | claimed |
| US-4144397-A | Preparation of 2-aryl-propionic acids by direct coupling utilizing a mixed magnesium halide complex | SYNTEX CORPORATION (US) | 1979-03-13 | — | — | US | claimed |