SCHEMBL335804

SCHEMBL335804

CCCCCCCCCCCCBr.[MgH2]

nearest known ligand 0.57

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.57
THRB P10828 1/20 0.57
DNM1 Q05193 6/20 0.42
ALDH1A1 P00352 3/20 0.42
LMNA P02545 2/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
HSD17B10 Q99714 1/20 0.42
SLC22A1 O15245 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL592867 1.00 TSHR (0.57) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL19385435 1.00 TSHR (0.57) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL11694103 1.00 TSHR (0.57) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL4514648 1.00 TSHR (0.57) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL4517239 1.00 TSHR (0.57) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL1784070 1.00
SCHEMBL8139520 1.00 TSHR (0.57) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL4219652 1.00 TSHR (0.57) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL597810 1.00
SCHEMBL842302 1.00 TSHR (0.57) TSHRTHRBDNM1ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 142 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113717019-B Continuous flow reaction method for asymmetric allyl alkylation reaction 哈尔滨工业大学(深圳) 2024-12-31 CN claimed
CN-115583863-B Asymmetric allyl alkylation reaction method 哈尔滨工业大学(深圳) 2023-10-31 CN claimed
CN-115583863-A Method for asymmetric allyl alkylation reaction 哈尔滨工业大学(深圳) 2023-01-10 CN claimed
CN-113717019-A Continuous flow reaction method for asymmetric allyl alkylation reaction 哈尔滨工业大学(深圳) 2021-11-30 CN claimed
US-20260102348-A1 COMPOUND OR SALT THEREOF AND LIPID PARTICLES FUJIFILM CORPORATION (JP) 2026-04-16 US disclosed
US-12508226-B2 Lipid composition FUJIFILM CORPORATION (JP) 2025-12-30 US disclosed
US-20250249123-A1 LIPIDS AND COMPOSITIONS THEREOF GENERATION BIO CO. 2025-08-07 US disclosed
US-12370143-B2 Compound or salt thereof and lipid particles FUJIFILM CORPORATION (JP) 2025-07-29 US disclosed
EP-4328309-B1 LIPID COMPOSITION FUJIFILM CORP (JP) 2025-07-02 EP disclosed
US-12285525-B2 Compound or salt thereof and lipid particles FUJIFILM CORPORATION (JP) 2025-04-29 US disclosed
US-12263228-B2 Lipids and compositions thereof GENERATION BIO CO. (US) 2025-04-01 US disclosed
CN-116172975-B Lipid particle, nucleic acid drug comprising same, and composition for nucleic acid delivery 富士胶片株式会社 2025-03-28 CN disclosed
WO-1992019610-A1 2- AND 5-ALKYL AND PHENYL SUBSTITUTED 4-(1-HYDROXY, 1-ACYLOXY OR 1-CARBAMOYLOXY)-5-HYDROXY-2(5H)-FURANONES AS ANTI-INFLAMMATORY AGENTS ALLERGAN, INC. (US) 1992-11-12 WO disclosed
US-5082954-A Intermediates and processes for preparing 4-substituted 2-5(H)-furanones as anti-inflammatory agents ALLERGAN, INC. (US) 1992-01-21 US disclosed
US-5045564-A Calcium channel antagonists ALLERGAN, INC. (US) 1991-09-03 US disclosed
US-5013850-A 4-ethyl and 4-ethenyl-5-hydroxy-2(5H)-furanones substituted on alpha carbon of the ethyl or ethenyl side chain with a long chain alkyl group and on the beta carbon with a polar group, as anti-inflammatory agents ALLERGAN, INC. (US) 1991-05-07 US disclosed
EP-0372940-A2 Anti-inflammatory 2-furanones ALLERGAN, INC (US) 1990-06-13 EP disclosed
US-4611071-A Metal alkyl process ETHYL CORPORATION (US) 1986-09-09 US disclosed
US-4507241-A Method for the hydrocarbylation of naphthoquinone derivatives E. I. DU PONT DE NEMOURS AND COMPANY (US) 1985-03-26 US disclosed
US-4065444-A LOW TEMPERATURE IMPACT STRENGTH UNIROYAL, INC. (US) 1977-12-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12370143-B2 Compound or salt thereof and lipid particles NR1H3, NR1H2, LDLR TSHR 999/4885THRB 2183/4885DNM1 1564/4885
US-12285525-B2 Compound or salt thereof and lipid particles NR1H3, NR1H2, LDLR TSHR 999/4885THRB 2183/4885DNM1 1564/4885
US-12263228-B2 Lipids and compositions thereof C1R, LIPG, LRBA TSHR 2035/4885THRB 1569/4885DNM1 1428/4885
US-20260102348-A1 COMPOUND OR SALT THEREOF AND LIPID PARTICLES LDLR, NR1H3, NR1H2 TSHR 1103/4885THRB 1305/4885DNM1 1101/4885
US-20250249123-A1 LIPIDS AND COMPOSITIONS THEREOF C1R, LIPG, LRBA TSHR 2035/4885THRB 1569/4885DNM1 1428/4885
US-12508226-B2 Lipid composition APOB, NAF1, SLC27A1 TSHR 1216/4885THRB 1398/4885DNM1 264/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.