Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 10/20 | 0.63 |
| ▸ | CYP11B1 | P15538 | 8/20 | 0.60 |
| ▸ | CYP11B2 | P19099 | 7/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19541845 | 0.84 | CYP19A1 (0.60) | CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL19541843 | 0.81 | CYP19A1 (0.57) | CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL15720237 | 0.79 | CYP11B1 (0.65) | CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL24844791 | 0.79 | CYP19A1 (0.48) | CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL29239323 | 0.77 | TBXAS1 (0.54) | CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL11494543 | 0.77 | CYP19A1 (0.46) | CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL9156397 | 0.77 | KDM4E (0.53) | CYP19A1 | |
| SCHEMBL11481840 | 0.76 | CYP19A1 (0.45) | CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL13105206 | 0.76 | CYP11B1 (0.58) | CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL11082155 | 0.75 | CYP11B1 (1.00) | CYP19A1CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015111080-A2 | NOVEL PROCESS FOR THE PREPARATION OF DOLUTEGRAVIR AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF | LAURUS LABS PRIVATE LIMITED (IN) | 2015-07-30 | — | — | WO | disclosed |