Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16941383 | 0.84 | BRD4 (0.39) | BRD4LMNAGAAMEN1ALDH1A1 | |
| SCHEMBL15596530 | 0.84 | BRD4 (0.39) | BRD4LMNAGAAMEN1ALDH1A1 | |
| SCHEMBL15595028 | 0.77 | GCK (0.38) | BRD4LMNAGAAKDM4E | |
| SCHEMBL15596523 | 0.75 | GSK3B (0.44) | BRD4LMNAGAAMEN1ALDH1A1 | |
| SCHEMBL3293755 | 0.73 | BRD4 (0.60) | BRD4LMNAGAAMEN1ALDH1A1 | |
| SCHEMBL16946149 | 0.71 | SMYD3 (0.36) | BRD4MEN1KMT2AHSD17B2 | |
| SCHEMBL4969089 | 0.70 | BRD4 (0.52) | BRD4GAAMEN1ALDH1A1KMT2A | |
| SCHEMBL4968331 | 0.67 | BRD4 (0.44) | BRD4LMNAGAAMEN1ALDH1A1 | |
| SCHEMBL4967583 | 0.67 | BRD4 (0.44) | BRD4LMNAGAAMEN1ALDH1A1 | |
| SCHEMBL4967580 | 0.67 | BRD4 (0.44) | BRD4LMNAGAAMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2882739-B1 | NEW ANTIBACTERIAL COMPOUNDS | JANSSEN SCIENCES IRELAND UC (IE) | 2017-05-03 | — | — | EP | disclosed |
| US-9315522-B2 | Antibacterial compounds | JANSSEN SCIENCES IRELAND UC (IE) | 2016-04-19 | — | — | US | disclosed |
| US-9296760-B2 | Antibacterial compounds | JANSSEN SCIENCES IRELAND UC (IE) | 2016-03-29 | — | — | US | disclosed |
| US-20150225424-A1 | Antibacterial compounds | JANSSEN SCIENCES IRELAND UC (IE) | 2015-08-13 | — | — | US | disclosed |
| US-20150210719-A1 | ANTIBACTERIAL COMPOUNDS | JANSSEN SCIENCES IRELAND US (IE) | 2015-07-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150210719-A1 | ANTIBACTERIAL COMPOUNDS | FAR1, GAA, ECI1 | BRD4 1924/4885LMNA 3299/4885GAA 2/4885 |
| US-20150225424-A1 | Antibacterial compounds | FAR1, GAA, ECI1 | BRD4 1924/4885LMNA 3299/4885GAA 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.