ECI1

Enoyl-CoA delta isomerase 1, mitochondrial · P42126 · ECI1 on Sugi Atlas →

0 patent compounds predicted against ECI1, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to ECI1 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Clinical Evaluation of the Effect of Metformin in Sepsis PHASE3UNKNOWN
Phase III Trial of Coenzyme Q10 in Mitochondrial Disease PHASE3COMPLETED
Acetylcarnitine and Insulin Sensitivity PHASE2COMPLETED
Atorvastatin, L-Carnitine and Non-Alcoholic Steatohepatitis PHASE2UNKNOWN
A Study of Bezafibrate in Mitochondrial Myopathy PHASE2COMPLETED
Efficacy and Safety of the Treatment of Pyruvate Dehydrogenase Deficiency Patients With Glycerol Phenylbutyrate (RAVICTI) PHASE2RECRUITING
Metabolic Cofactor Supplementation in Alzheimer's Disease (AD) and Parkinson's Disease (PD) Patients PHASE2COMPLETED
Effect of Bezafibrate on Muscle Metabolism in Patients With Fatty Acid Oxidation Defects PHASE2COMPLETED
Does Clinical Treatment of Mitochondrial Dysfunction Impact Autism Spectrum Disorder (ASD)? PHASE1UNKNOWN
Nicotinamide Riboside and Mitochondrial Biogenesis nanCOMPLETED
GDF-15 as a Biomarker for Mitochondrial Disease nanCOMPLETED
Effects of Parenteral L-carnitine Supplementation in Premature Neonates nanCOMPLETED
Genomic Profiling of Mitochondrial Disease - Imaging Analysis for Precise Mitochondrial Medicine nanCOMPLETED
Nephroprotective Effects of Carnitine and (PDE5) Inhibitor Agent Against Contrast Media-induced Nephropathy (CMN) nanUNKNOWN
Fatty Acid Oxidation Defects and Insulin Sensitivity nanCOMPLETED
Abnormalities in the Effects of Insulin and Exercise on Glucose- and Lipid Metabolism in Obesity and Type 2 Diabetes nanCOMPLETED
Tissue Sample Study for Mitochondrial Disorders nanENROLLING_BY_INVITATION
Lifestyle Intervention in Preparation for Pregnancy (LIPP) nanCOMPLETED
Relationship Between Mitochondrial Dysfunction and Fatique in Cancer Patients Following External Beam Radiation Therapy nanCOMPLETED
Exercise-mediated Rescue of Mitochondrial Dysfunctions Driving Insulin Resistance nanCOMPLETED
Systemic Biomarkers of Brain Injury From Hyperammonemia nanRECRUITING
The RolE oF Androgen Excess in MUscle Energy MetaboLism in Women With PolyCystic Ovary Syndrome (REFUEL PCOS) Study 2 nanUNKNOWN
Dynamics of Muscle Mitochondria in Type 2 Diabetes Exercise nanCOMPLETED
North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC) nanRECRUITING
Drug Repurposing for Mitochondrial Disorders Using iPSCs Derived Neural Cells nanRECRUITING
Acute Infection in Mitochondrial Disease: Metabolism, Infection and Immunity nanRECRUITING
Impact of Iron Deficiency and Its Correction on Mitochondrial Metabolism of the Cardiomyocyte (MitoCardioFer) nanCOMPLETED
Mitochondrial Dysfunctions Driving Insulin Resistance nanCOMPLETED
Longitudinal Study of Mitochondrial Hepatopathies nanSUSPENDED
Human Mitochondrial Stress-driven Obesity Resistance nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a ECI1 binder may also engage these)

ProteinNameSimilarity
P23965 0.990 P23965 →
P42125 0.988 P42125 →
F1NB38 0.974 F1NB38 →
Q3MIE0 0.970 Q3MIE0 →
Q9D7J9 0.969 Q9D7J9 →
Q2HJD5 0.966 Q2HJD5 →
Q96DC8 0.965 Q96DC8 →
F1R6N4 0.965 F1R6N4 →
Q9NTX5 0.964 Q9NTX5 →
Q9D9V3 0.963 Q9D9V3 →
Q6AYG5 0.960 Q6AYG5 →
Q5R4W0 0.960 Q5R4W0 →
Q8R164 0.959 Q8R164 →
ECH1 Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial 0.957 landscape →
Q5RFG0 0.951 Q5RFG0 →
LPCAT1 Lysophosphatidylcholine acyltransferase 1 0.949 landscape →
Q9ER88 0.949 Q9ER88 →
P47823 0.948 P47823 →
Q5I0L3 0.948 Q5I0L3 →
Q5R824 0.948 Q5R824 →
Q0V8R7 0.948 Q0V8R7 →
Q5R514 0.948 Q5R514 →
P84850 0.948 P84850 →
Q9BV79 0.948 Q9BV79 →
Q5HZQ8 0.947 Q5HZQ8 →
E1BNQ4 0.947 E1BNQ4 →
Q8BGT5 0.947 Q8BGT5 →
P13439 0.947 P13439 →
O35459 0.947 O35459 →
EIF2B5 Translation initiation factor eIF2B subunit epsilon 0.947 landscape →