SCHEMBL16947980

SCHEMBL16947980

CC(=O)[C@@H](N)CCCCNC(=O)COCCOCCNC(=O)CCCCCCCCCCCCCCC(=O)O

nearest known ligand 0.53

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 8/20 0.53
▸ EPHX2 P34913 3/20 0.41
▸ ADRA1A P35348 1/20 0.40
▸ NOD1 Q9Y239 1/20 0.40
▸ EPOR P19235 2/20 0.40
▸ ITGB3 P05106 1/20 0.38
▸ ITGA2B P08514 1/20 0.38
▸ FOLH1 Q04609 2/20 0.37
▸ TLR2 O60603 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23839871 0.99 GLP1R (0.52) GLP1REPHX2ADRA1ANOD1EPOR
SCHEMBL16638274 0.91 GLP1R (0.67) GLP1RNOD1FOLH1
SCHEMBL24891117 0.91 GLP1R (0.67) GLP1RNOD1FOLH1
SCHEMBL15357538 0.91 GLP1R (0.67) GLP1RNOD1FOLH1
SCHEMBL24890886 0.91 GLP1R (0.67) GLP1RNOD1FOLH1
SCHEMBL16947959 0.91 GLP1R (0.67) GLP1RNOD1FOLH1
SCHEMBL16638273 0.91 GLP1R (0.67) GLP1RNOD1FOLH1
SCHEMBL16947828 0.91 GLP1R (0.67) GLP1RNOD1FOLH1
SCHEMBL19034928 0.91 GLP1R (0.55) GLP1REPHX2NOD1EPORITGB3
SCHEMBL19034958 0.91 GLP1R (0.55) GLP1REPHX2NOD1EPORITGB3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150210745-A1 Double-Acylated GLP-1 Derivatives with a Linker NOVO NORDISK AS (DK) 2015-07-30 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150210745-A1 Double-Acylated GLP-1 Derivatives with a Linker GLP1R, VIP, IAPP GLP1R 1/4885EPHX2 2295/4885ADRA1A 1937/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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