Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCAT | P04180 | 12/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ABL1 | P00519 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.43 |
| ▸ | SMO | Q99835 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16948785 | 0.90 | LCAT (0.51) | LCAT | |
| SCHEMBL16803493 | 0.87 | LCAT (0.45) | LCATKDM4EABL1LMNAGPR119 | |
| SCHEMBL16948831 | 0.86 | LCAT (0.56) | LCAT | |
| SCHEMBL18138559 | 0.81 | LCAT (0.75) | LCAT | |
| SCHEMBL18138551 | 0.81 | LCAT (0.75) | LCAT | |
| SCHEMBL18138562 | 0.81 | LCAT (0.75) | LCAT | |
| SCHEMBL18138647 | 0.81 | LCAT (0.75) | LCAT | |
| SCHEMBL18138646 | 0.81 | LCAT (0.75) | LCAT | |
| SCHEMBL16948620 | 0.79 | LCAT (0.56) | LCAT | |
| SCHEMBL16648612 | 0.78 | LCAT (0.72) | LCAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015111545-A1 | CONDENSED PYRAZOLE DERIVATIVE | 第一三共株式会社 | 2015-07-30 | — | — | WO | disclosed |