Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCAT | P04180 | 5/20 | 0.45 |
| ▸ | CXCR3 | P49682 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16948816 | 0.87 | LCAT (0.56) | LCATKDM4EGPR119ABL1LMNA | |
| SCHEMBL16803503 | 0.80 | LCAT (0.61) | LCAT | |
| SCHEMBL16803480 | 0.80 | LCAT (0.61) | LCAT | |
| SCHEMBL16803487 | 0.80 | LCAT (0.61) | LCAT | |
| SCHEMBL16948785 | 0.78 | LCAT (0.51) | LCAT | |
| SCHEMBL16948831 | 0.73 | LCAT (0.56) | LCAT | |
| SCHEMBL16803465 | 0.70 | DPP4 (0.47) | LCATKDM4EGPR119ABL1LMNA | |
| SCHEMBL16803456 | 0.70 | LCAT (0.67) | LCAT | |
| SCHEMBL16948834 | 0.69 | LCAT (0.49) | LCATCXCR3 | |
| SCHEMBL18138551 | 0.69 | LCAT (0.75) | LCAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015087995-A1 | CYCLOALKYL OR HETEROCYCLYL PYRAZOLOPYRIDINE DERIVATIVE | 第一三共株式会社 | 2015-06-18 | — | — | WO | disclosed |