Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 20/20 | 0.56 |
| ▸ | PGR | P06401 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3023346 | 0.84 | AR (0.43) | ARPGR | |
| SCHEMBL1996075 | 0.78 | AR (0.73) | AR | |
| SCHEMBL221383 | 0.78 | AR (0.62) | ARPGR | |
| SCHEMBL1003776 | 0.78 | AR (0.58) | ARPGR | |
| SCHEMBL16953011 | 0.77 | AR (0.53) | ARPGR | |
| SCHEMBL409108 | 0.76 | AR (0.74) | ARPGR | |
| SCHEMBL1128325 | 0.76 | AR (0.74) | ARPGR | |
| SCHEMBL1226983 | 0.76 | AR (0.56) | ARPGR | |
| SCHEMBL1643378 | 0.76 | AR (0.56) | ARPGR | |
| SCHEMBL950544 | 0.76 | AR (0.68) | ARPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3168214-B1 | SUBSTITUTED 2-THIOXO-IMIDAZOLIDIN-4-ONES AND SPIRO ANALOGUES THEREOF, ACTIVE ANTI-CANCER INGREDIENT, PHARMACEUTICAL COMPOSITION, MEDICINAL PREPARATION, METHOD FOR TREATING PROSTATE CANCER | R PHARM OVERSEAS INC (US) | 2019-04-24 | — | — | EP | claimed |
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |