Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | XBP1 | P17861 | 1/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | RARA | P10276 | 1/20 | 0.32 |
| ▸ | RARB | P10826 | 1/20 | 0.32 |
| ▸ | RARG | P13631 | 1/20 | 0.32 |
| ▸ | GCK | P35557 | 1/20 | 0.32 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.32 |
| ▸ | FOS | P01100 | 2/20 | 0.31 |
| ▸ | JUN | P05412 | 2/20 | 0.31 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.31 |
| ▸ | ACACB | O00763 | 2/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16957056 | 0.86 | MEN1 (0.37) | MAPTPOLBHPGDXBP1NR1H4 | |
| SCHEMBL16952753 | 0.85 | MAPT (0.36) | MAPTPOLBHPGDXBP1NR1H4 | |
| SCHEMBL16954766 | 0.83 | TP53 (0.37) | ALDH1A1KAT6ATSHRKDM4ETP53 | |
| SCHEMBL16960252 | 0.83 | ALDH1A1 (0.35) | MAPTPOLBHPGDXBP1NR1H4 | |
| SCHEMBL16957061 | 0.83 | MAOB (0.36) | MAPTPOLBHPGDXBP1NR1H4 | |
| SCHEMBL16953386 | 0.83 | F2 (0.35) | MAPTPOLBHPGDXBP1NR1H4 | |
| SCHEMBL16956610 | 0.83 | HPGD (0.40) | MAPTPOLBHPGDXBP1ALDH1A1 | |
| SCHEMBL16952431 | 0.81 | HPGD (0.37) | MAPTPOLBHPGDXBP1NR1H4 | |
| SCHEMBL16956509 | 0.81 | MAPT (0.34) | MAPTPOLBHPGDXBP1NR1H4 | |
| SCHEMBL16957419 | 0.81 | FFAR4 (0.39) | MAPTPOLBHPGDXBP1NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |