Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | ERN1 | O75460 | 1/20 | 0.40 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16951502 | 0.85 | MAPT (0.43) | TSHRALDH1A1ERN1SMN1; SMN2L3MBTL1 | |
| SCHEMBL16958951 | 0.83 | TSHR (0.38) | TSHRTDP1ALDH1A1ARERN1 | |
| SCHEMBL16961097 | 0.83 | TSHR (0.61) | TSHRTDP1ALDH1A1ERN1GPR35 | |
| SCHEMBL16957718 | 0.83 | TSHR (0.51) | TSHRTDP1ALDH1A1ARERN1 | |
| SCHEMBL29686473 | 0.81 | TSHR (0.54) | TSHRTDP1ALDH1A1ARGPR35 | |
| SCHEMBL7111424 | 0.81 | TSHR (0.54) | TSHRTDP1ALDH1A1ARGPR35 | |
| SCHEMBL16955472 | 0.79 | TSHR (0.44) | TSHRTDP1ALDH1A1ERN1GPR35 | |
| SCHEMBL16958092 | 0.79 | TSHR (0.44) | TSHRTDP1ALDH1A1ERN1GPR35 | |
| SCHEMBL16954032 | 0.79 | TSHR (0.44) | TSHRTDP1ALDH1A1ERN1GPR35 | |
| SCHEMBL16955342 | 0.79 | TSHR (0.44) | TSHRTDP1ALDH1A1ERN1GPR35 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |