Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ERN1 | O75460 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16952972 | 0.85 | TSHR (0.43) | TSHRERN1TDP1GPR35GLA | |
| SCHEMBL16951963 | 0.83 | TSHR (0.45) | TSHRERN1TDP1GPR35GLA | |
| SCHEMBL16955816 | 0.80 | TSHR (0.39) | TSHRERN1TDP1GPR35GLA | |
| SCHEMBL16951502 | 0.80 | MAPT (0.43) | TSHRERN1ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL16956062 | 0.80 | TSHR (0.41) | TSHRERN1TDP1GPR35GLA | |
| SCHEMBL16951761 | 0.79 | ADORA2A (0.36) | TDP1ALDH1A1HTTMAPTNPSR1 | |
| SCHEMBL16951043 | 0.77 | KMT2A (0.31) | — | |
| SCHEMBL16955342 | 0.77 | TSHR (0.44) | TSHRERN1TDP1GPR35GLA | |
| SCHEMBL16960104 | 0.77 | KCNK3 (0.37) | ALDH1A1GAA | |
| SCHEMBL16956056 | 0.77 | GABRA1 (0.37) | PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |