Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16952933 | 0.86 | GAA (0.34) | ALDH1A1GAAL3MBTL1HSD17B10LMNA | |
| SCHEMBL16957212 | 0.84 | ALDH1A1 (0.36) | ALDH1A1GAAL3MBTL1HSD17B10LMNA | |
| SCHEMBL15388910 | 0.84 | TSHR (0.41) | ALDH1A1GAAL3MBTL1HSD17B10LMNA | |
| SCHEMBL16958806 | 0.83 | KDM4E (0.34) | ALDH1A1GAAL3MBTL1HSD17B10LMNA | |
| SCHEMBL16959178 | 0.83 | ALDH1A1 (0.33) | ALDH1A1GAAL3MBTL1HSD17B10LMNA | |
| SCHEMBL16950829 | 0.81 | ALDH1A1 (0.39) | ALDH1A1GAALMNANOTUMTSHR | |
| SCHEMBL7508041 | 0.77 | AR (0.43) | ALDH1A1GAAL3MBTL1HSD17B10LMNA | |
| SCHEMBL16952724 | 0.77 | TSHR (0.50) | ALDH1A1GAAL3MBTL1LMNATSHR | |
| SCHEMBL16952177 | 0.77 | ALDH1A1 (0.36) | ALDH1A1GAAL3MBTL1HSD17B10LMNA | |
| SCHEMBL16954482 | 0.76 | GAA (0.35) | ALDH1A1GAAL3MBTL1HSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |