Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 3/20 | 0.52 |
| ▸ | CD274 | Q9NZQ7 | 3/20 | 0.52 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9654043 | 0.83 | PDCD1 (0.48) | PDCD1CD274APOBEC3GCYP3A4CYP2C19 | |
| SCHEMBL16961430 | 0.83 | GABRA1 (0.48) | PDCD1CD274HPGDLMNAGABRA1 | |
| SCHEMBL6424004 | 0.81 | PDCD1 (0.64) | PDCD1CD274APOBEC3GMEN1KMT2A | |
| SCHEMBL2652419 | 0.79 | PDCD1 (0.53) | PDCD1CD274CYP3A4CYP2C9HPGD | |
| SCHEMBL16958912 | 0.79 | DAO (0.36) | PDCD1CD274CYP3A4CYP2C19CYP2C9 | |
| SCHEMBL2887974 | 0.78 | PDCD1 (0.47) | PDCD1CD274CYP3A4HPGDLMNA | |
| SCHEMBL16953307 | 0.77 | GABRA1 (0.41) | PDCD1CD274APOBEC3GCYP3A4CYP2C19 | |
| SCHEMBL16952332 | 0.77 | APOBEC3G (0.39) | PDCD1CD274APOBEC3GCYP3A4CYP2C19 | |
| SCHEMBL16962383 | 0.77 | APOBEC3G (0.39) | PDCD1CD274APOBEC3GCYP3A4CYP2C19 | |
| SCHEMBL16950306 | 0.75 | GABRA1 (0.40) | PDCD1CD274APOBEC3GHPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |