Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | HMGCR | P04035 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.31 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | HTR1D | P28221 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16950657 | 0.90 | HMGCR (0.34) | HMGCRHTR1D | |
| SCHEMBL16956135 | 0.85 | GABRA2 (0.38) | NPC1HPGDRAB9AMAPK1HTT | |
| SCHEMBL16950379 | 0.84 | HPGD (0.45) | NPC1HPGDRAB9AMAPK1HTT | |
| SCHEMBL16954999 | 0.82 | HMGCR (0.35) | HMGCR | |
| SCHEMBL28249284 | 0.82 | HPGD (0.47) | NPC1HPGDRAB9AMAPK1HTT | |
| SCHEMBL16954777 | 0.80 | HPGD (0.42) | NPC1HPGDRAB9AMAPK1HTT | |
| SCHEMBL16962597 | 0.79 | HPGD (0.41) | NPC1HPGDRAB9AMAPK1HTT | |
| SCHEMBL16957421 | 0.77 | NPC1 (0.48) | NPC1HPGDRAB9AMAPK1HTT | |
| SCHEMBL16960721 | 0.76 | HTT (0.39) | NPC1HPGDRAB9AMAPK1HTT | |
| SCHEMBL16958982 | 0.76 | HPGD (0.39) | NPC1HPGDRAB9AMAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |