Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN8A | Q9UQD0 | 5/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16479208 | 0.87 | SCN8A (0.46) | SCN8ACHRM2LMNACHRM1ALOX15 | |
| SCHEMBL16955205 | 0.87 | SCN8A (0.42) | SCN8ALMNATSHRKCNH2HCRTR1 | |
| SCHEMBL16952410 | 0.83 | CHRM2 (0.38) | SCN8ACHRM2LMNACHRM1ALOX15 | |
| SCHEMBL16952357 | 0.81 | S1PR1 (0.40) | SCN8AHTR1AL3MBTL1KDM4E | |
| SCHEMBL16961972 | 0.80 | CHRM2 (0.36) | CHRM2LMNACHRM1ALOX15TSHR | |
| SCHEMBL16961971 | 0.80 | CHRM2 (0.36) | CHRM2LMNACHRM1ALOX15TSHR | |
| SCHEMBL16958650 | 0.80 | CHRM2 (0.43) | CHRM2LMNACHRM1ALOX15TSHR | |
| SCHEMBL14827795 | 0.80 | SMN1; SMN2 (0.46) | SCN8ACHRM2LMNACHRM1ALOX15 | |
| SCHEMBL16959757 | 0.79 | CHRM2 (0.39) | CHRM2LMNACHRM1ALOX15TSHR | |
| SCHEMBL16959755 | 0.79 | CHRM2 (0.36) | CHRM2LMNACHRM1ALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |