Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN8A | Q9UQD0 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.37 |
| ▸ | GRK6 | P43250 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16952414 | 0.87 | SCN8A (0.43) | SCN8AL3MBTL1KDM4EHCRTR1HCRTR2 | |
| SCHEMBL16479216 | 0.86 | SCN8A (0.42) | SCN8AL3MBTL1PDK2ALDH1A1HPGD | |
| SCHEMBL16952357 | 0.83 | S1PR1 (0.40) | SCN8AL3MBTL1ALDH1A1KDM4ES1PR1 | |
| SCHEMBL16955203 | 0.81 | L3MBTL1 (0.39) | L3MBTL1PDK2ALDH1A1MAPTTDP1 | |
| SCHEMBL2522911 | 0.81 | ALDH1A1 (0.47) | SCN8AL3MBTL1ALDH1A1MAPTTDP1 | |
| SCHEMBL16962084 | 0.80 | SMN1; SMN2 (0.42) | SCN8AALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL16707502 | 0.79 | SCN8A (0.44) | SCN8AALDH1A1KDM4EHPGDCYP1A2 | |
| SCHEMBL16959937 | 0.79 | KCNK3 (0.40) | L3MBTL1PDK2ALDH1A1MAPTHPGD | |
| SCHEMBL16954501 | 0.79 | ALDH1A1 (0.40) | L3MBTL1PDK2ALDH1A1MAPTTDP1 | |
| SCHEMBL16954498 | 0.79 | PDK2 (0.40) | L3MBTL1PDK2ALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |