Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.49 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CASR | P41180 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL84441 | 0.86 | TSHR (0.53) | TSHRLOXL2PTGS1PTGS2CYP4F2 | |
| SCHEMBL10609523 | 0.84 | TSHR (0.52) | TSHRLOXL2PTGS1PTGS2CYP4F2 | |
| SCHEMBL26453747 | 0.84 | TSHR (0.52) | TSHRLOXL2PTGS1PTGS2CYP4F2 | |
| SCHEMBL246026 | 0.84 | TSHR (0.52) | TSHRLOXL2PTGS1PTGS2CYP4F2 | |
| SCHEMBL698948 | 0.84 | TSHR (0.52) | TSHRLOXL2PTGS1PTGS2CYP4F2 | |
| SCHEMBL26453761 | 0.84 | TSHR (0.52) | TSHRLOXL2PTGS1PTGS2CYP4F2 | |
| SCHEMBL16952057 | 0.83 | LOXL2 (0.47) | TSHRLOXL2PTGS1PTGS2CYP4F2 | |
| SCHEMBL16956227 | 0.83 | CYP4F2 (0.54) | TSHRLOXL2PTGS1PTGS2CYP4F2 | |
| SCHEMBL20466894 | 0.83 | TSHR (0.50) | TSHRLOXL2PTGS1PTGS2CYP4F2 | |
| SCHEMBL9522934 | 0.83 | TSHR (0.50) | TSHRLOXL2PTGS1PTGS2CYP4F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |