Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 1/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.39 |
| ▸ | IKBKB | O14920 | 9/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 2/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.32 |
| ▸ | CHUK | O15111 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16959918 | 0.84 | PDCD1 (0.36) | PDCD1CD274IKBKBNOTUMHTR2C | |
| SCHEMBL16954608 | 0.83 | PDCD1 (0.35) | PDCD1CD274IKBKBNOTUMHTR2C | |
| SCHEMBL16954852 | 0.83 | NOTUM (0.38) | IKBKBNOTUMHTR2CHTR6 | |
| SCHEMBL16959723 | 0.77 | HTR2C (0.44) | PDCD1CD274IKBKBHTR2CHTR6 | |
| SCHEMBL16950595 | 0.74 | NOTUM (0.38) | NOTUMHTR2CHCRTR2HCRTR1 | |
| SCHEMBL16950958 | 0.74 | HTR2C (0.46) | NOTUMHTR2CHTR6 | |
| SCHEMBL16956713 | 0.74 | PDCD1 (0.40) | PDCD1CD274IKBKBGAAHTR6 | |
| SCHEMBL2785452 | 0.73 | DRD4 (0.42) | PDCD1CD274HTR6 | |
| SCHEMBL16953156 | 0.73 | NOTUM (0.37) | NOTUMHTR2CHCRTR2HCRTR1 | |
| SCHEMBL20532511 | 0.73 | KDM4E (0.47) | PDCD1CD274OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |