Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 1/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | IKBKB | O14920 | 1/20 | 0.30 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | HTR6 | P50406 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16953189 | 0.85 | NOTUM (0.34) | NOTUMHTR6 | |
| SCHEMBL16952889 | 0.83 | PDCD1 (0.39) | PDCD1CD274NOTUMHCRTR2GAA | |
| SCHEMBL16952506 | 0.78 | HTR2C (0.40) | NOTUMHTR2CHTR6 | |
| SCHEMBL16959918 | 0.78 | PDCD1 (0.36) | PDCD1CD274NOTUMHCRTR2CNR2 | |
| SCHEMBL16952964 | 0.77 | NOTUM (0.33) | NOTUMHCRTR2HCRTR1 | |
| SCHEMBL16962251 | 0.77 | NOTUM (0.33) | NOTUM | |
| SCHEMBL16956098 | 0.77 | NOTUM (0.39) | NOTUM | |
| SCHEMBL16960028 | 0.77 | TAS1R3 (0.34) | NOTUM | |
| SCHEMBL16955359 | 0.77 | CHRNA1 (0.38) | HCRTR2HTR6 | |
| SCHEMBL16954610 | 0.77 | HCRTR1 (0.32) | NOTUMHCRTR2HCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |