Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 4/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 4/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 4/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 3/20 | 0.32 |
| ▸ | HTR1A | P08908 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16962253 | 0.81 | — | — | |
| SCHEMBL16950597 | 0.80 | ADRA2A (0.36) | ADRA2AADRA2BADRA2CPDK2PDK4 | |
| SCHEMBL16950960 | 0.80 | HTR2C (0.43) | ADRA2AADRA2BADRA2CPDK2PDK4 | |
| SCHEMBL16958709 | 0.79 | ADRA2A (0.35) | ADRA2AADRA2BADRA2CPDK2PDK4 | |
| SCHEMBL16952157 | 0.79 | NOTUM (0.36) | ADRA2AADRA2BADRA2CPDK2PDK4 | |
| SCHEMBL16955738 | 0.78 | — | — | |
| SCHEMBL16955619 | 0.76 | ADRA2A (0.34) | ADRA2AADRA2BADRA2CPDK2PDK4 | |
| SCHEMBL16952945 | 0.76 | ADRA2A (0.34) | ADRA2AADRA2BADRA2CPDK2PDK4 | |
| SCHEMBL16962728 | 0.76 | ADRA2A (0.37) | ADRA2AADRA2BADRA2CPDK2PDK4 | |
| SCHEMBL16955804 | 0.75 | IDO1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |