Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TTR | P02766 | 1/20 | 0.43 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16950788 | 0.87 | KDM4E (0.42) | LMNAKDM4ETP53MAPTKMT2A | |
| SCHEMBL16954673 | 0.83 | LMNA (0.46) | LMNAKDM4ETP53MAPTKMT2A | |
| SCHEMBL16952305 | 0.81 | CYP1A1 (0.39) | KDM4EMAPTKMT2AMEN1TTR | |
| SCHEMBL16959089 | 0.80 | LMNA (0.44) | LMNAKDM4ETP53MAPTKMT2A | |
| SCHEMBL16953691 | 0.80 | LMNA (0.61) | LMNAKDM4ETP53MAPTKMT2A | |
| SCHEMBL16957671 | 0.80 | LMNA (0.46) | LMNAKDM4ETP53MAPTKMT2A | |
| SCHEMBL16953162 | 0.80 | CYP4F2 (0.61) | LMNAKDM4ETP53MAPTKMT2A | |
| SCHEMBL16951633 | 0.78 | ACACB (0.33) | MAPTKMT2ASMN1; SMN2MEN1POLB | |
| SCHEMBL16957669 | 0.78 | CYP4F2 (0.44) | LMNAKDM4ETP53MAPTKMT2A | |
| SCHEMBL16956887 | 0.78 | CYP4F2 (0.44) | LMNAKDM4ETP53MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |