Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 4/20 | 0.83 |
| ▸ | GAA | P10253 | 1/20 | 0.81 |
| ▸ | RECQL | P46063 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | GID4 | Q8IVV7 | 3/20 | 0.59 |
| ▸ | KDM1A | O60341 | 2/20 | 0.58 |
| ▸ | DRD2 | P14416 | 1/20 | 0.52 |
| ▸ | DRD1 | P21728 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL1695318 | 1.00 | PRCP (0.83) | PRCPGAARECQLTSHRNPSR1 | |
| Urea SCHEMBL28007088 | 0.92 | PRCP (0.81) | PRCPGAARECQLTSHRNPSR1 | |
| SCHEMBL2227395 | 0.92 | PRCP (0.81) | PRCPGAARECQLTSHRNPSR1 | |
| Carbamic Acid SCHEMBL9226170 | 0.92 | PRCP (0.81) | PRCPGAARECQLTSHRNPSR1 | |
| SCHEMBL28288395 | 0.92 | PRCP (0.81) | PRCPGAARECQLTSHRNPSR1 | |
| SCHEMBL327233 | 0.91 | PRCP (1.00) | PRCPGAARECQLGID4KDM1A | |
| SCHEMBL29478499 | 0.91 | PRCP (1.00) | PRCPGAARECQLGID4KDM1A | |
| SCHEMBL30721685 | 0.91 | PRCP (1.00) | PRCPGAARECQLGID4KDM1A | |
| SCHEMBL12046710 | 0.91 | PRCP (1.00) | PRCPGAARECQLGID4KDM1A | |
| SCHEMBL325083 | 0.91 | PRCP (1.00) | PRCPGAARECQLGID4KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3067353-B1 | A PROCESS FOR THE PREPARATION OF SOLIFENACIN SALTS AND THEIR INCLUSION INTO PHARMACEUTICAL DOSAGE FORMS | KRKA D D NOVO MESTO (SI) | 2017-11-22 | — | — | EP | disclosed |
| EP-3067353-A1 | A PROCESS FOR THE PREPARATION OF SOLIFENACIN SALTS AND THEIR INCLUSION INTO PHARMACEUTICAL DOSAGE FORMS | KRKA, D.D., Novo Mesto (SI) | 2016-09-14 | — | — | EP | disclosed |
| EP-2310387-A2 | A PROCESS FOR THE PREPARATION OF SOLIFENACIN SALTS AND THEIR INCLUSION INTO PHARMACEUTICAL DOSAGE FORMS | KRKA, D.D., Novo Mesto (SI) | 2011-04-20 | — | — | EP | disclosed |
| WO-2010012459-A2 | A PROCESS FOR THE PREPARATION OF SOLIFENACIN SALTS AND THEIR INCLUSION INTO PHARMACEUTICAL DOSAGE FORMS | KRKA, D.D., NOVO MESTO (SI) | 2010-02-04 | — | — | WO | disclosed |