Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.34 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.34 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.34 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.34 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.34 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.32 |
| ▸ | HTR2A | P28223 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12197672 | 0.86 | CYP1A2 (0.39) | RECQLHRH4PSEN1PSEN2APH1B | |
| SCHEMBL16959685 | 0.82 | HRH4 (0.33) | RECQLHRH4PSEN1PSEN2APH1B | |
| SCHEMBL10039364 | 0.80 | RECQL (0.36) | RECQLHRH4PSEN1PSEN2APH1B | |
| SCHEMBL4547940 | 0.80 | RECQL (0.36) | RECQLHRH4PSEN1PSEN2APH1B | |
| SCHEMBL16960712 | 0.80 | PSEN1 (0.46) | RECQLPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL16952139 | 0.79 | PSEN1 (0.38) | RECQLHRH4PSEN1PSEN2APH1B | |
| SCHEMBL24869062 | 0.78 | PDE2A (0.48) | RECQLHRH4PSEN1PSEN2APH1B | |
| SCHEMBL16957963 | 0.78 | KCNH2 (0.43) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL24869041 | 0.78 | MEN1 (0.41) | RECQLHRH4PSEN1PSEN2APH1B | |
| SCHEMBL16952125 | 0.78 | PSEN1 (0.34) | PSEN1PSEN2APH1BNCSTNAPH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |