Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16951890 | 0.83 | CA1 (0.47) | CA12CA1CA2CA7CA9 | |
| SCHEMBL16962794 | 0.81 | KMT2A (0.43) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL232793 | 0.80 | CA12 (0.62) | CA12CA1CA2CA7CA9 | |
| SCHEMBL16953984 | 0.79 | MAPT (0.48) | CA12CA1CA2CA7CA9 | |
| SCHEMBL15865412 | 0.78 | MAPT (0.48) | CA12CA1CA2CA7CA9 | |
| SCHEMBL27932793 | 0.78 | MAPT (0.63) | CA12CA1CA2CA7CA9 | |
| SCHEMBL16950908 | 0.77 | CYP1A1 (0.44) | CA12CA1CA2CA7CA9 | |
| SCHEMBL16950905 | 0.77 | MAPT (0.41) | CA12CA1CA2CA7CA9 | |
| SCHEMBL16952054 | 0.77 | CYP2D6 (0.46) | CA12CA1CA2CA7CA9 | |
| SCHEMBL16959674 | 0.77 | ALDH1A1 (0.47) | CA1CA2CA9MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |