Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 2/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | GPR3 | P46089 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16950575 | 0.88 | PDE2A (0.43) | PDE2AHRH4GPR3L3MBTL1PPARG | |
| SCHEMBL16955240 | 0.81 | CYP2D6 (0.39) | — | |
| SCHEMBL16955507 | 0.81 | NQO1 (0.42) | TSHR | |
| SCHEMBL16961511 | 0.78 | GPR3 (0.39) | PDE2AHRH4CTSSCTSKGPR3 | |
| SCHEMBL23055180 | 0.78 | PDE2A (0.47) | PDE2AHRH4CTSSCTSKGPR3 | |
| SCHEMBL16952904 | 0.78 | PDE2A (0.42) | PDE2AGPR3LMNAL3MBTL1PPARD | |
| SCHEMBL16951176 | 0.77 | HRH4 (0.40) | PDE2AHRH4CTSSCTSKLMNA | |
| SCHEMBL16959893 | 0.76 | PDE2A (0.49) | PDE2AGPR3SCN10A | |
| SCHEMBL16961512 | 0.76 | GPR3 (0.41) | PDE2AHRH4CTSSCTSKGPR3 | |
| SCHEMBL16958881 | 0.76 | PDE2A (0.42) | PDE2AHRH4GPR3LMNASCN10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |