Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 12/20 | 0.61 |
| ▸ | CES2 | O00748 | 2/20 | 0.40 |
| ▸ | CES1 | P23141 | 2/20 | 0.40 |
| ▸ | CA3 | P07451 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16960982 | 0.80 | NFE2L2 (0.39) | NFE2L2MAOB | |
| SCHEMBL1148194 | 0.79 | NFE2L2 (0.63) | NFE2L2CES2CES1CA3CA6 | |
| SCHEMBL1148197 | 0.79 | NFE2L2 (0.63) | NFE2L2CES2CES1CA3CA6 | |
| SCHEMBL3251490 | 0.77 | NFE2L2 (0.61) | NFE2L2CES2CES1CA3CA6 | |
| SCHEMBL14541331 | 0.77 | NFE2L2 (0.61) | NFE2L2CES2CES1CA3CA6 | |
| SCHEMBL16951286 | 0.77 | NFE2L2 (0.61) | NFE2L2CES2CES1CA3CA6 | |
| SCHEMBL704659 | 0.77 | NFE2L2 (0.55) | NFE2L2CES2CES1CA3CA6 | |
| SCHEMBL704660 | 0.77 | NFE2L2 (0.55) | NFE2L2CES2CES1CA3CA6 | |
| SCHEMBL20995856 | 0.76 | NFE2L2 (1.00) | NFE2L2 | |
| SCHEMBL21996542 | 0.76 | NFE2L2 (1.00) | NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |