Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.37 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16959216 | 0.84 | FFAR4 (0.43) | PTGS2FFAR4 | |
| SCHEMBL25372383 | 0.83 | FFAR4 (0.42) | FFAR4GPR84PPARAPRKCAPRKCD | |
| SCHEMBL30694771 | 0.83 | FFAR4 (0.42) | FFAR4GPR84PPARAPRKCAPRKCD | |
| SCHEMBL16958426 | 0.81 | PCSK9 (0.40) | PTGS2NPC1HPGDMAPK1HTT | |
| SCHEMBL16954175 | 0.81 | PCSK9 (0.38) | PTGS2NPC1HPGDMAPK1HTT | |
| SCHEMBL2089811 | 0.80 | FFAR4 (0.44) | FFAR4GPR84PRKCAPRKCD | |
| SCHEMBL9311583 | 0.80 | HPGD (0.56) | PTGS2NPC1HPGDMAPK1HTT | |
| SCHEMBL16954729 | 0.80 | PTGS2 (0.38) | PTGS2NPC1HPGDMAPK1HTT | |
| SCHEMBL16955432 | 0.80 | PTGS2 (0.62) | PTGS2NPC1HPGDMAPK1HTT | |
| SCHEMBL16954178 | 0.79 | CNR1 (0.35) | PTGS2NPC1HPGDMAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |